- 3-METHYL-1H-INDAZOLE
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- $1.00 / 1KG
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2019-07-06
- CAS:3176-62-3
- Min. Order: 1KG
- Purity: 95%
- Supply Ability: 500KG
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| | 3-METHYL-1H-INDAZOLE Basic information |
| Product Name: | 3-METHYL-1H-INDAZOLE | | Synonyms: | 3-METHYL-1H-INDAZOLE;1H-Indazole, 3-methyl-;1-Propanone,1-(3,9-dichlorophenyl)-;Benzenamine,N,N,3,9-tetramethyl- | | CAS: | 3176-62-3 | | MF: | C8H8N2 | | MW: | 132.16 | | EINECS: | 1533716-785-6 | | Product Categories: | Indazole | | Mol File: | 3176-62-3.mol |  |
| | 3-METHYL-1H-INDAZOLE Chemical Properties |
| Melting point | 113°C | | Boiling point | 234.08°C (rough estimate) | | density | 1.1083 (rough estimate) | | refractive index | 1.6013 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | pka | 14.39±0.40(Predicted) |
| Hazard Codes | Xn | | Risk Statements | 22 | | HS Code | 2933998090 |
| | 3-METHYL-1H-INDAZOLE Usage And Synthesis |
| Description | 3-Methyl-1H-indazole is a heterocyclic alkyl compound containing nitrogen and three methyl groups. It is used as an intermediate in the synthesis of other compounds. It has been shown to have anti-inflammatory properties in vitro. It also inhibits neutrophil chemotaxis and may be used to treat inflammatory diseases such as trigeminal neuralgia or heart disease. 3-Methyl-1H-indazole has also been shown to inhibit histamine H3 receptor activity, which may account for its effects on eye diseases and bladder cancer. | | Uses | 3-Methyl-1H-indazole is an intermediate compound. It can be used as an organic synthesis reagent for the preparation of 3-methyl-1H-indazol-5-amine and 3-methyl-5-nitro-1H-indazole compounds. In addition, the 3-Methyl-1H-indazole derivatives (1a-1d and 2a-2d) have antimicrobial effects, both having antibacterial activity against Bacillus subtilis and Escherichia coli[1]. | | Synthesis Reference(s) | Journal of Heterocyclic Chemistry, 25, p. 1817, 1988 DOI: 10.1002/jhet.5570250641
Synthesis, p. 982, 1984 | | References | [1] FARRUKH SHAIKH. Synthesis and evaluation of antibacterial activity of novel 3-methyl-1H-indazole derivatives[J]. Intelligent Pharmacy, 2024. DOI:10.1016/j.ipha.2023.09.003. |
| | 3-METHYL-1H-INDAZOLE Preparation Products And Raw materials |
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