Company Name: |
Alabiochem Tech.Co., Ltd.
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Tel: |
0512-58900862 400-0707518 |
Email: |
sales@alabiochem.com |
Products Intro: |
Product Name:Proteasome Inhibitor XVI CAS:389064-25-9 Purity:>98% HPLC Package:5mg; 25mg; 100mg; 1g; 5g; 25g;100g Remarks:Peptide
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Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:AdaAhxLVS - CAS 389064-25-9 - Calbiochem
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Company Name: |
Alabiotech Inc.
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Tel: |
001-619-354-5251 |
Email: |
sales@alabiotech-e.com |
Products Intro: |
Product Name:Proteasome Inhibitor XVI CAS:389064-25-9 Purity:>98% Package:25mg;100mg;500mg;1g;5g;10g Remarks:B0131
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| Proteasome Inhibitor XVI Basic information |
Product Name: | Proteasome Inhibitor XVI | Synonyms: | Proteasome Inhibitor XVI;AdaAhxLVS - CAS 389064-25-9 - Calbiochem;L-Leucinamide, N-[1-oxo-6-[[1-oxo-6-[[1-oxo-6-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]hexyl]amino]hexyl]amino]hexyl]-L-leucyl-N-[(1S)-3-methyl-1-[(1E)-2-(methylsulfonyl)ethenyl]butyl]- | CAS: | 389064-25-9 | MF: | C50H88N6O8S | MW: | 933.33 | EINECS: | | Product Categories: | | Mol File: | 389064-25-9.mol | |
| Proteasome Inhibitor XVI Chemical Properties |
Boiling point | 1161.4±65.0 °C(Predicted) | density | 1.096±0.06 g/cm3(Predicted) | storage temp. | -20C | form | Off-white powder | pka | 13.41±0.46(Predicted) |
| Proteasome Inhibitor XVI Usage And Synthesis |
General Description | A cell-permeable, peptide vinyl sulfone that acts as a potent, irreversible inhibitor of proteasome activity. Covalently modifies the catalytically active β-subunits of the proteasome. Shown to inhibit the chymotrypsin-like (10-50 nM), trypsin-like (1-5 μM), and the peptidyl glutamyl peptide hydrolyzing (PGPH) (0.5-1 μM) activities of purified 20S proteasomes from rabbit muscle. Inhibits proteasomal degradation of deglycosylated MHC HLA-A2 heavy chain in US11+ cells (~50 μM). | Biochem/physiol Actions | Cell permeable: yes |
| Proteasome Inhibitor XVI Preparation Products And Raw materials |
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