Regorafenib Impurity 16

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Regorafenib Impurity 16 Basic information
Product Name:Regorafenib Impurity 16
Synonyms:N-Desmethyl N-Hydroxymethyl Regorafenib;Regorafenib N-Desmethyl N-Hydroxymethyl Impurity;2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-(hydroxymethyl)-;Hydroxymethyl Regorafenib
CAS:1343498-71-4
MF:C21H15ClF4N4O4
MW:498.81
EINECS:
Product Categories:
Mol File:1343498-71-4.mol
Regorafenib Impurity 16 Structure
Regorafenib Impurity 16 Chemical Properties
Melting point >160°C (dec.)
Boiling point 550.8±50.0 °C(Predicted)
density 1.553±0.06 g/cm3(Predicted)
storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka12.05±0.70(Predicted)
form Solid
color White
Stability:Light Sensitive
Safety Information
MSDS Information
Regorafenib Impurity 16 Usage And Synthesis
UsesN-Desmethyl N-Hydroxymethyl Regorafenib is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.
Regorafenib Impurity 16 Preparation Products And Raw materials
Tag:Regorafenib Impurity 16(1343498-71-4) Related Product Information
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide 2-Pyridinecarboxamide, 4-[2-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl- N-Desmethyl Regorafenib N-Oxide (M5 Metabolite) Regorafenib Impurity 13 4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide Regorafenib Impurity 9 Regorafenib Impurity 10 N-Desmethyl Regorafenib 4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide Regorafenib Impurity 6 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]phenoxy]-N-methyl- Regorafenib Impurity 17 4-(4-amino-3-(4-amino-3-(4-amino-3-fluorophenoxy)phenoxy)phenoxy)-N-methylpicolinamide INDEX NAME NOT YET ASSIGNED