MKC3946

MKC3946 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:MKC-3946
CAS:1093119-54-0
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:MKC-3946
CAS:1093119-54-0
Purity:>98% Package:300mg Remarks:BOC Sciences also provides custom synthesis services for MKC-3946.
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:MKC3946
CAS:1093119-54-0
Purity:98% Package:5mg Remarks:V3985
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:MKC3946
CAS:1093119-54-0
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: LEAPCHEM CO., LTD.
Tel: +86-852-30606658
Email: market18@leapchem.com
Products Intro: Product Name:MKC3946
CAS:1093119-54-0
Purity:0 Package:1g; 5g; 25g; 1kg; 5kg; 25kg Remarks:0
MKC3946 Basic information
Product Name:MKC3946
Synonyms:MKC3946;MKC3946;MKC-3946;MKC 3946;1-Naphthalenecarboxaldehyde, 2-hydroxy-6-[5-[(4-methyl-1-piperazinyl)carbonyl]-2-thienyl]-;2-Hydroxy-6-(5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl)-1-naphthaldehyde;Inositol requiring enzyme 1,inhibit,IRE1,MKC3946,Inhibitor,MKC 3946,MKC-3946
CAS:1093119-54-0
MF:C21H20N2O3S
MW:380.46
EINECS:
Product Categories:
Mol File:1093119-54-0.mol
MKC3946 Structure
MKC3946 Chemical Properties
Boiling point 591.6±50.0 °C(Predicted)
density 1.337±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO:20.0(Max Conc. mg/mL);52.57(Max Conc. mM)
form A crystalline solid
pka8.18±0.50(Predicted)
Safety Information
MSDS Information
MKC3946 Usage And Synthesis
Biological ActivityMKC3946 is a soluble inhibitor of the IRE1α endoribonuclease domain, causing moderate growth inhibition in multiple myeloma cell lines without toxic effects on normal monocytes.
in vivoIn an in vivo model of endoplasmic reticulum stress, MKC-3946 inhibits cleavage of XBP1 and significantly inhibits myeloma cell growth.
target< /table>
TargetValue
IRE1α endoribonuclease
()
MKC3946 Preparation Products And Raw materials
Tag:MKC3946(1093119-54-0) Related Product Information
MKC8866 ISRIB MK-8998 MK-4101 MK8745 MK-3903 mk-1064 (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide MK 0557 MK-0812 (Succinate) MKC9989 GSK2656157 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine