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Orelabrutinib

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Orelabrutinib Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:Orelabrutinib
CAS:1655504-04-3
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Orelabrutinib；ICP-022
CAS:1655504-04-3
Purity:98.00% Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:Orelabrutinib
CAS:1655504-04-3
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Products Intro: Product Name:Ingenol
CAS:1655504-04-3
Purity:99% Package:5KG;1KG
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:Orelabrutinib
CAS:1655504-04-3
Purity:0.98 Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing

Orelabrutinib manufacturers

  • Orelabrutinib USP/EP/BP
  • Orelabrutinib USP/EP/BP pictures
  • $1.10 / 1g
  • 2021-07-06
  • CAS:1655504-04-3
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons Min
Orelabrutinib Basic information
Product Name:Orelabrutinib
Synonyms::6-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)-3-Pyridinecarboxamide;Orelabrutinib;ICP-022;3-Pyridinecarboxamide, 6-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)-;Orelabrutinib USP/EP/BP;6-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide;Malignancies,Btk,ICP 022,inhibit,antineoplastic,Inhibitor,chronic,small,Bruton tyrosine kinase,lymphocytic leukemia,cell,Orelabrutinib,ICP022;Orelabrutinib (ICP-022)
CAS:1655504-04-3
MF:C26H25N3O3
MW:427.49
EINECS:
Product Categories:
Mol File:1655504-04-3.mol
Orelabrutinib Structure
Orelabrutinib Chemical Properties
Boiling point 646.3±55.0 °C(Predicted)
density 1.213±0.06 g/cm3(Predicted)
pka14.80±0.50(Predicted)
Safety Information
MSDS Information
Orelabrutinib Usage And Synthesis
DescriptionOrelabrutinib is a small molecule inhibitor of Bruton's tyrosine kinase with potential antineoplastic activity.
UsesOrelabrutinib has been previously approved to treat  patients with relapsed or refractory (R/R) mantle cell lymphoma and R/R  chronic lymphocytic leukemia/small lymphocytic lymphoma.
Biological ActivityOrelabrutinib (ICP-022) is a potent, orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK).
Mechanism of actionUpon administration, orelabrutinib binds to and inhibits the activity of BTK. This prevents both the activation of the B-cell antigen receptor (BCR)  signaling pathway and BTK-mediated activation of downstream survival  pathways, inhibiting the growth of malignant B-cells that overexpress  BTK.
target
TargetValue
BTK
()
Orelabrutinib Preparation Products And Raw materials
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