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1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol

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1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:GNE 2861
CAS:1394121-05-1
Purity:97.03% Package:1mg;36USD|2mg;50USD|5mg;79USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:GNE-2861
CAS:1394121-05-1
Purity:98%+ Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
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Email: tp@aladdinsci.com
Products Intro: Product Name:GNE 2861
CAS:1394121-05-1
Purity:>=98%(HPLC) Package:$97.9/5mg;$162.9/10mg;$325.9/25mg;$543.9/50mg;$979.9/100mg;Bulk package Remarks:98%(HPLC)
Company Name: WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.  
Tel: 17702719238 18971495150;
Email: sales@sun-shinechem.com
Products Intro: Product Name:GNE-2861
CAS:1394121-05-1
Purity:98% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g
Company Name: ChemShuttle, Inc.  
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Products Intro: Product Name:1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol
CAS:1394121-05-1
Purity:95% Package:5mg;25mg;100mg;500mg;1g;5g;10g;25g;50g;100g;250g;500g;kg…

1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol manufacturers

  • GNE 2861
  • GNE 2861 pictures
  • $36.00 / 1mg
  • 2025-11-09
  • CAS:1394121-05-1
  • Min. Order:
  • Purity: 99.07%
  • Supply Ability: 10g
1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Basic information
Product Name:1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol
Synonyms:1-[2-[3-(2-aminopyrimidin-4-yl)-2-(2-methoxyethylamino)benzimidazol-5-yl]ethynyl]cyclohexan-1-ol;1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol;GNE-2861; GNE 2861; GNE2861.;1-[2-[1-(2-Amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]cyclohexanol;181525;GNE-2861;Cyclohexanol, 1-[2-[1-(2-amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]-;p21 activated kinases,inhibit,Inhibitor,PAK,GNE 2861,GNE-2861,GNE2861
CAS:1394121-05-1
MF:C22H26N6O2
MW:406.48
EINECS:
Product Categories:APIS
Mol File:1394121-05-1.mol
1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Structure
1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Chemical Properties
storage temp. Store at -20°C
solubility DMSO:82.83(Max Conc. mg/mL);203.77(Max Conc. mM)
Ethanol:40.65(Max Conc. mg/mL);100.0(Max Conc. mM)
form A solid
color White to yellow
Safety Information
MSDS Information
1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Usage And Synthesis
Biological ActivityGNE 2861 is a PAK inhibitor with selectivity for group II. It inhibits PAK4, PAK5 and PAK6 with IC50 values of 7.5, 36 and 126 nM, respectively.
in vitro

GNE-2861 is compound 4 from the reference.

target

IC50: 7.5 nM (PAK4), 36 nM (PAK5), 126 nM (PAK6)

storageStore at -20°C
1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol Preparation Products And Raw materials
Tag:1-((1-(2-aminopyrimidin-4-yl)-2-((2-methoxyethyl)amino)-1H-benzo[d]imidazol-6-yl)ethynyl)cyclohexanol(1394121-05-1) Related Product Information
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