| Company Name: |
Alinda Chemical Ltd.
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| Tel: |
+7 (495) 672-17-08 |
| Email: |
sale@alinda.ru |
| Products Intro: |
CAS:326901-92-2
Package:1mg Remarks:C13H8Cl2N2O2S
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| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:WDR5-IN-6
CAS:326901-92-2
Purity:98% Package:5mg Remarks:S34058
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| | 1-((2,5-dichlorophenyl)sulfonyl)-1H-benzo[d]imidazole Basic information |
| | 1-((2,5-dichlorophenyl)sulfonyl)-1H-benzo[d]imidazole Chemical Properties |
| Boiling point | 525.7±60.0 °C(Predicted) | | density | 1.55±0.1 g/cm3(Predicted) | | pka | -0.28±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | 1-((2,5-dichlorophenyl)sulfonyl)-1H-benzo[d]imidazole Usage And Synthesis |
| Uses | WDR5-IN-6 is a WDR5 inhibitor, targeting to WBM site. WDR5-IN-6 inhibits cell proliferation of neuroblastoma cell lines with potent anti-tumor activity. WDR5-IN-6 shows high synergy with OICR-9429 (HY-16993), a WDR5 inhibitor targeting to WIN site. WDR5-IN-6 can be used for reasearch in neuroblastoma[1]. | | References | [1] Han QL, et al. Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol Sin. 2023 Apr;44(4):877-887. DOI:10.1038/s41401-022-00999-z |
| | 1-((2,5-dichlorophenyl)sulfonyl)-1H-benzo[d]imidazole Preparation Products And Raw materials |
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