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BuforMin Hydrochloride

BuforMin Hydrochloride Suppliers list
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:BUTYL-BIGUANIDE HYDROCHLORIDE
CAS:1190-53-0
Purity:0.99 Package:5KG;1KG
Company Name: BOC Sciences
Tel: 1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Buformin hydrochloride
CAS:1190-53-0
Purity:95% Package:1G;10G;100G Remarks:Buformin hydrochloride is a hydrochloride form of Buformin, clinically used for diabetes mellitus, it is known to improve resistance to insulin in patients by suppressing the expression of glyceraldeh
Company Name: HENAN BON INDUSTRIAL CO.,LTD
Tel: 0371-55170695
Email: info@hnbon.com
Products Intro: CAS:1190-53-0
Purity:0.99 Package:25KG;5KG;1KG;500G
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: 86-18523575427
Email: sales@conier.com
Products Intro: Product Name:buformin hydrochloride
CAS:1190-53-0
Purity:99% Package:1kg
Company Name: career henan chemical co
Tel: 0086-371-86658258 13203830695
Email: factory@coreychem.com
Products Intro: Product Name:Buformin Hydrochloride
CAS:1190-53-0
Purity:>98% Package:1KG;9.8USD

BuforMin Hydrochloride manufacturers

BuforMin Hydrochloride Basic information
Product Name:BuforMin Hydrochloride
Synonyms:1-Butylbigyanidine hydrochloride;1-Butylbiguanide Hydrochloride;N-ButylidodicarboniMidic DiaMide Hydrochloride;PanforMin;Sindiatil;TideMol;Ziavetine;Adebit
CAS:1190-53-0
MF:C6H16ClN5
MW:193.68
EINECS:214-723-6
Product Categories:Amines;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:1190-53-0.mol
BuforMin Hydrochloride Structure
BuforMin Hydrochloride Chemical Properties
Melting point 177-179?C
storage temp. Inert atmosphere,Store in freezer, under -20°C
CAS DataBase Reference1190-53-0
Safety Information
Risk Statements 22-43-36
Safety Statements 36/39-46
HS Code 29212900
ToxicityLD50 i.p. in mice: 380 mg/kg (Rikimaru)
MSDS Information
BuforMin Hydrochloride Usage And Synthesis
Chemical PropertiesWhite Solid
OriginatorSilubin,Protochemie,Switz.
UsesBuforMin Hydrochloride is a biguanide derivative with antihyperglycemic activity. It delays absorption of glucose from the gastrointestinal tract, increases insulin sensitivity and glucose utilization in peripheral cells, and inhibits hepatic gluconeogenesis. BuforMin Hydrochloride has also been examined for antitumor activity due to its ability to disrupt the unfolded protein response transcription program during glucose deprivation, which induces cell death in glucose-deprived tumor cells.
UsesBuformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase.
Manufacturing Process105.6 g of n-butylamine hydrochloride and 79.3 g of dicyandiamide were ground intimately and mixed. The mixture was heated by means of an oil bath, gradually with stirring, and after thirty minutes when the internal temperature had reached 150°C, an exothermic reaction ensued with internal pressure rising to 178°C. The reaction mixture was removed from the oil bath until the internal temperature had fallen to 150°C and then heating was resumed at 150°C for one hour. The cooled fusion mixture was dissolved in 3 liters of acetonitrile and on cooling n-butyl-biguanide hydrochloride precipitated.
Therapeutic FunctionAntidiabetic
BuforMin Hydrochloride Preparation Products And Raw materials
Raw materialsBUTYLAMINE HYDROCHLORIDE-->Dicyandiamide
Tag:BuforMin Hydrochloride(1190-53-0) Related Product Information
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