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Acetyl tributyl citrate

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Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 86-0551-65418684 18949823763
Products Intro: Product Name:Acetyl tributyl citrate
Purity:99.9% Package:1KG;5USD
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Products Intro: Product Name:Acetyl tributyl citrate
Purity:99% Package:15/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Acetyl tributyl citrate
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:77-90-7
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Acetyl tributyl citrate

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Acetyl tributyl citrate Basic information
Product Name:Acetyl tributyl citrate
Synonyms:ACETYL TRIBUTYL CITRATE;ACETYL TRI-N-BUTYL CITRATE;1,2,3-Propanetricarboxylic acid, 2-acetoxy-, tributyl ester;1,2,3-Propanetricarboxylicacid,2-(acetyloxy)-,tributylester;2-(Acetyloxy)-1,2,3-propane tricarboxylic acid, tributyl ester;2,3-propanetricarboxylicacid,2-(acetyloxy)-tributylester;acetylcitricacidtributylester;2-Acetoxy-1,2,3-propanetricarboxylic acid tributyl ester
Product Categories:-;Industrial/Fine Chemicals;Functional Materials;Hydroxycarboxylic Acid Esters (Plasticizer);Plasticizer;Amino ester;Aliphatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Building Blocks;C12 to C63;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Esters
Mol File:77-90-7.mol
Acetyl tributyl citrate Structure
Acetyl tributyl citrate Chemical Properties
Melting point -59 °C
Boiling point 327 °C
density 1.05 g/mL at 25 °C(lit.)
vapor pressure 0.26 psi ( 20 °C)
refractive index n20/D 1.443(lit.)
Fp >230 °F
storage temp. Store below +30°C.
solubility Not miscible with water, miscible with ethanol (96 per cent) and with methylene chloride.
form neat
Water Solubility <0.1 g/100 mL
FreezingPoint -80℃
JECFA Number630
BRN 2303316
CAS DataBase Reference77-90-7(CAS DataBase Reference)
NIST Chemistry Reference1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester(77-90-7)
EPA Substance Registry System1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester(77-90-7)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS TZ8330000
HS Code 29181500
Hazardous Substances Data77-90-7(Hazardous Substances Data)
MSDS Information
Acetyl tributyl citrate English
SigmaAldrich English
ACROS English
Acetyl tributyl citrate Usage And Synthesis
Chemical Propertiesclear colorless liquid
Chemical PropertiesAcetyltributyl citrate is a clear, odorless, practically colorless, oily liquid.
Chemical PropertiesTributyl acetylcitrate has a very faint, sweet, herbaceous odor. At high levels (e.g., 1000 ppm emulsion in water), it has a mild, fruity, nondescript flavor.
UsesLabelled Tributyl O-Acetylcitrate (T772950). Topical pharmaceutical formulation anesthetic surfactant ester.
Usesplasticizer flavoring agent
DefinitionAqueous-based pharmaceutical coat- ings.
PreparationFrom citric acid via the tributyl ester followed by acetylation.
Production MethodsAcetyltributyl citrate is prepared by the esterification of citric acid with butanol followed by acylation with acetic anhydride.
Pharmaceutical ApplicationsAcetyltributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings, including capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release and enteric formulations.
Safety ProfileWhen heated to decomposition it emits acrid smoke and irritating fumes. ADD750
Safetyand films intended for direct food contact. It is also used in selfadhesive thin films used for topical delivery systems. It is generally regarded as a relatively nontoxic and nonirritating material. However, ingestion of large quantities may be harmful.
LD50 (cat, oral): >50 mL/kg
LD50 (mouse, IP): >4 g/kg
LD50 (rat, oral): >31.5 g/kg
storageAcetyltributyl citrate should be stored in a well-closed container in a cool, dry location at temperatures not exceeding 38℃. When stored in accordance with these conditions, acetyltributyl citrate is a stable product.
IncompatibilitiesAcetyltributyl citrate is incompatible with strong alkalis and oxidizing materials.
Regulatory StatusIncluded in FDA Inactive Ingredients Database (oral capsules and tablets). Included in nonparenteral medicines licensed in the UK. Approved in the USA for direct food contact in food films.
Acetyl tributyl citrate Preparation Products And Raw materials
Raw materials1-Butanol-->Citric acid
Tag:Acetyl tributyl citrate(77-90-7) Related Product Information
TRIMETHYL 1,2,3-PROPANETRICARBOXYLATE (R)-(+)-2-METHOXYPROPIONIC ACID Propyl isovalerate diethyl hydrogen 2-hydroxypropane-1,2,3-tricarboxylate n-Butyryl tri-n-hexyl citrate Acetyl tributyl citrate Triethyl acetyl citrate Triethyl citrate Calcium citrate CITRATE Acetylacetone Sildenafil citrate Zinc citrate Tributyl citrate Butyl levulinate Sodium citrate Ammonium citrate tribasic CLOMIFENE CITRATE