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1-Methyl-4-pyrazole boronic acid pinacol ester

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Company Name: China Synchem Technology Co.,Ltd.
Tel: 0552-4929304
Email: sales@cnsynchem.com
Products Intro: Product Name:1-Methylpyrazole-4-boronic acid pinacol ester
CAS:761446-44-0
Purity:1kg;50kg;100kg;1t Package:98%min Remarks:commercial scale
Company Name: Accela ChemBio Inc.
Tel: (+1)-858-699-3322
Email: info@accelachem.com
Products Intro: Product Name:1-Methylpyrazole-4-boronic Acid Pinacol Ester
CAS:761446-44-0
Purity:97+% Package:100g;10g;1g;25g;5g Remarks:SY003667
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:1-Methyl-4-pyrazole boronic acid pinacol ester
CAS:761446-44-0
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd.
Tel: +86-10-60279497 +86(0)15646567669
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Products Intro: Product Name:1-Methyl-4-pyrazole boronic acid pinacol ester
CAS:761446-44-0
Purity:98%99% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:761446-44-0
Purity:99% Package:500G;1KG;5KG;25KG

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1-Methyl-4-pyrazole boronic acid pinacol ester Basic information
Product Name:1-Methyl-4-pyrazole boronic acid pinacol ester
Synonyms:1-Methy-4-(4,4,5,5,-tertamethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-Methylpyrazole-4-boronic acid pinacol ester (Related Reference);1-MethylPyrazole-4-Boronic acid Pinacolate;1-methyl-4-(4-tetramethyl-1-dioxaborolan-2-yl)-1H-;1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-;1-METHYL- 4-PYRAZOLEBORONIC ACID PINACOL ESTER;1-METHYL-4-(4,4,5,5-TERAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE;1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-
CAS:761446-44-0
MF:C10H17BN2O2
MW:208.07
EINECS:616-293-9
Product Categories:Organoborons;Pyrazole;Boronic acid;Heterocyclic Building Blocks;Boronate Esters;Boronic Acids and Derivatives;Chemical Synthesis;Heteroaryl Boronate Esters;Organometallic Reagents
Mol File:761446-44-0.mol
1-Methyl-4-pyrazole boronic acid pinacol ester Structure
1-Methyl-4-pyrazole boronic acid pinacol ester Chemical Properties
Melting point 59-64 °C(lit.)
Boiling point 308.3±15.0 °C(Predicted)
density 1.05±0.1 g/cm3(Predicted)
storage temp. Refrigerator (+4°C)
pka2.09±0.10(Predicted)
form Crystals
color Off-white to yellow
Water Solubility Slightly soluble in water.
InChIKeyUCNGGGYMLHAMJG-UHFFFAOYSA-N
CAS DataBase Reference761446-44-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,F,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
Hazard Note Irritant/Flammable
TSCA No
HazardClass IRRITANT
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
1-Methyl-4-pyrazole boronic acid pinacol ester Usage And Synthesis
Chemical PropertiesWhite to light yellow crystal powde
Uses1-Methyl-4-pyrazole boronic acid pinacol ester is a reagent used for:Suzuki-Miyaura cross-coupling reactions1,2,3• ;Transesterification reactions4Reagent used for preparation of• ;Aminothiazoles as γ-secretase modulators5• ;Amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy6• ;Pyridine derivatives as TGF-β1 and activin A signalling inhibitors7• ;MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer8.
Usessuzuki reaction
1-Methyl-4-pyrazole boronic acid pinacol ester Preparation Products And Raw materials
Raw materialsTetrahydrofuran-->Potassium hydroxide-->n-Butyllithium-->Iodomethane-->Trimethyl borate-->Methyl bromide-->Pinacol-->5A molecular sieve-->4-Bromopyrazole
Tag:1-Methyl-4-pyrazole boronic acid pinacol ester(761446-44-0) Related Product Information
TRIS(TRIMETHYLSILYL) PHOSPHATE Zolpidem Metazachlor Methyl salicylate Pyraclostrobin Methanol Methylparaben Mefenpyr-diethyl Pinacol Pyrazole Tolyltriazole Methyl acrylate Basic Violet 1 Tribenuron methyl METSULFURON METHYL Methyl Kresoxim-methyl AcidEster