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| Product Name: | QX-314 | | Synonyms: | 2-[(2,6-Dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium;QX-314;LIDOCAINE N-ETHYL BROMIDE;N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE;QX-314.Br;QX-314 bromide (N-Ethyllidocaine bromide);N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM BROMIDE;N-(2,6-DIMETHYLPHENYL)ACETAMIDE-2-TRIETHYLAMMONIUM BROMIDE;QX-314;QX 314 BROMIDE | | CAS: | 21306-56-9 | | MF: | C16H27N2O+ | | MW: | 263.4 | | EINECS: | | | Product Categories: | Sodium channel;Ion Channels | | Mol File: | 21306-56-9.mol |  |
| | QX-314 Chemical Properties |
| Melting point | 220 - 222°C | | storage temp. | Desiccate at RT | | solubility | DMSO (Slightly), Methanol (Slightly) | | color | White to Off-White | | Specific Activity | 40-60 Ci/mmol | | Solvent | Ethanol:water (1:1) | | Concentration | 1 mCi/ml |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | QX-314 Usage And Synthesis |
| Uses | Blocker of voltage-activated sodium channels | | Uses | QX-314 bromide is a derivative of Lidocaine. It is a local anesthetic. | | Biological Activity | Membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na + channels. Intracellular QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons. |
| | QX-314 Preparation Products And Raw materials |
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