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Parthenolide

Parthenolide Suppliers list
Company Name: NanJing Spring & Autumn Biological Engineering CO., LTD.
Tel: 0086 13815430202
Email: sale02@cqherb.com
Products Intro: Product Name:Factory Price Parthenolide 20554-84-1
CAS:20554-84-1
Purity:98.00% HPLC Package:1g;93USD
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008615858145714
Email: fandachem@gmail.com
Products Intro: Product Name:(-)-Parthenolide
CAS:20554-84-1
Purity:As coa Package:As request Remarks:20554-84-1
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Parthenolide
CAS:20554-84-1
Purity:HPLC>=98% Package:20mg
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Parthenolide
CAS:20554-84-1
Purity:98% Package:1KG;2USD
Company Name: Biochempartner
Tel: 0086-13720134139
Email: candy@biochempartner.com
Products Intro: Product Name:Parthenolide
CAS:20554-84-1
Purity:98% HPLC LCMS Package:10G;20G

Lastest Price from Parthenolide manufacturers

  • Parthenolide
  • US $0.00 / mg
  • 2020-05-11
  • CAS:20554-84-1
  • Min. Order: 5mg
  • Purity: ≥98%(HPLC)
  • Supply Ability: 10 g
Parthenolide Basic information
Product Name:Parthenolide
Synonyms:Parthenolide, Tanacetum parthenium - CAS 20554-84-1 - Calbiochem;Factory Price Parthenolide 20554-84-1;Natural Plant Extracts Parthenolide 20554-84-1 High Purity HPLC>98%;Feverfew P.E Parthenlide;[1aR-(1aR*,4E,7aS*,10aS*,-10bR*)]-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;(1aR,4E,7aS,10aS,10bS)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;4,5α-Epoxy-6β-hydroxygermacra-1(10),11(13)-dien-12-oic acid γ-lactone;4,5alpha-epoxy-6beta-hydroxy-germacra-1(10),11(13)-dien-12-oic acid gamma-lactone
CAS:20554-84-1
MF:C15H20O3
MW:248.32
EINECS:692-532-0
Product Categories:inhibitor;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Sesqui-Terpenoids;Isoprenoid/terpenoidNeurotransmitters;Anti-Proliferative AgentsNutrition Research;Antitumor Agents;Biochemicals Found in Plants;Cancer Research;Others;Natural Product;Serotonergics;Prostanoid receptor and related
Mol File:20554-84-1.mol
Parthenolide Structure
Parthenolide Chemical Properties
Melting point 115-116 °C(lit.)
alpha D20 -81.4° (c = 1.04 in chloroform); D22 -71.4° (c = 0.220 in CH2Cl2)
Boiling point 394.1±42.0 °C(Predicted)
density 1.13±0.1 g/cm3(Predicted)
storage temp. 2-8°C
form White solid
Merck 14,7048
CAS DataBase Reference20554-84-1
Safety Information
Hazard Codes Xi,C,F
Risk Statements 11-34
Safety Statements 22-24/25-45-36/37/39-26-16
WGK Germany 3
RTECS LY4220000
HS Code 29322090
MSDS Information
ProviderLanguage
SigmaAldrich English
Parthenolide Usage And Synthesis
DescriptionParthenolide is an allergen in feverfew (Tanacetum parthenarium).
Chemical PropertiesWhite solid
UsesAntiinflammatory;MAP kinase inhibitor
UsesParthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium). It inhibits the growth of the promastigote form of L. amazonensis (IC50 = 3.6 μg/ml). Parthenolide also induces apoptosis in cancer cells, at least in part by inhibiting NF-κB- and STAT-mediated anti-apoptotic gene transcription. This compound has also been shown to block inflammation by inhibiting signaling through NF-κB. Inhibition of NF-κB by parthenolide can be achieved by direct binding of the pattern recognition receptor NOD2 by parthenolide.
DefinitionChEBI: A sesquiterpene lactone and active principle of Feverfew (Tanacetum parthenium).
Biological ActivityThe active principle of feverfew (Chrysanthemum parthenium), widely used as a herbal remedy for arthritis and migraine and as a febrifuge. Parthenolide is antisecretory, anti-inflammatory, spasmolytic and inhibits the release of 5-HT from blood platelets. Also inhibits generation of leukotriene B 4 and thromboxane B 2 .
Contact allergensParthenolide is a sesquiterpene lactone found Asteraceae- Compositae such as feverfew (Tanacetum parthenium Schultz-Bip.) or congress grass (Parthenium hysterophorus L.).
Parthenolide Preparation Products And Raw materials
Tag:Parthenolide(20554-84-1) Related Product Information
Kauniolide Tulipalin A Glycidyl methacrylate 2-BUTOXYETHYL ACRYLATE GLYCIDYL ACRYLATE CITRONELLYL BUTYRATE Allyl glycidyl ether Glycidyl butyrate METHYL TUBERATE ETHYL 6-METHYL-6-HEPTENOATE (E)-5-DECEN-1-YL ACETATE 5-ETHYL-3-METHYLENE-DIHYDRO-FURAN-2-ONE S-Glycidyl Acetate 1,2-EPOXY-5-HEXENE (S)-(+)-Glycidyl butyrate 2-N-BUTOXYETHYL METHACRYLATE Parthenolide Spironolactone