|
|
| | 4-(Trifluoromethoxy)benzyl bromide Basic information | | Uses |
| | 4-(Trifluoromethoxy)benzyl bromide Chemical Properties |
| Melting point | 22-24°C | | Boiling point | 82-84 °C10 mm Hg(lit.) | | density | 1.594 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.48(lit.) | | Fp | 202 °F | | storage temp. | Refrigerated. | | solubility | soluble in Chloroform, Methanol | | form | Liquid or Low Melting Solid | | Specific Gravity | 1.594 | | color | Clear faintly yellow | | Sensitive | Lachrymatory | | BRN | 2521451 | | CAS DataBase Reference | 50824-05-0(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-27-28-36/37/39-45 | | RIDADR | UN 3265 8/PG 2 | | WGK Germany | 3 | | Hazard Note | Corrosive/Lachrymatory | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29093090 |
| | 4-(Trifluoromethoxy)benzyl bromide Usage And Synthesis |
| Uses | 4-Trifluoromethoxybenzyl Bromide is a useful synthetic intermediate. It is used to prepare (nitro)[(trifluoromethoxy)benzyloxy]dihydroimidazo[2,1-b][1,3]oxazines with antitubercular activities. It is also used to synthesize tetrahydronaphthalenols with anti-allergic activities. | | Chemical Properties | Colorless to light yellow liqui | | Uses | 4-(Trifluoromethoxy)benzyl bromide may be used in the synthesis of bioreductive drug, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824). | | General Description | Polymerizations of 4-(trifluoromethoxy)benzyl bromide, via Friedel-Crafts polymerization using aluminum chloride as a catalyst has been reported. |
| | 4-(Trifluoromethoxy)benzyl bromide Preparation Products And Raw materials |
|