LY-3154207 manufacturers
- LY3154207
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- $432.00 / 5mg
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2024-10-28
- CAS:1638667-79-4
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | LY-3154207 Basic information |
| Product Name: | LY-3154207 | | Synonyms: | LY-3154207;2-(2,6-dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one;LY-3154207,LY3154207;Ethanone, 2-(2,6-dichlorophenyl)-1-[(1S,3R)-3,4-dihydro-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-2(1H)-isoquinolinyl]-;2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one , LY3154207;mevidalen | | CAS: | 1638667-79-4 | | MF: | C24H29Cl2NO3 | | MW: | 450.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1638667-79-4.mol |  |
| | LY-3154207 Chemical Properties |
| Boiling point | 628.4±55.0 °C(Predicted) | | density | 1.245±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 110 mg/mL (244.23 mM; Need ultrasonic) | | pka | 14.60±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | LY-3154207 Usage And Synthesis |
| Uses | LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor
positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM)[1]. | | References | [1] Hao J, Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Po DOI:10.1021/acs.jmedchem.9b01234 |
| | LY-3154207 Preparation Products And Raw materials |
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