| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:SNX0723
CAS:1073969-18-2
Purity:99.86% Package:1 mg;10 mg;100 mg;25 mg;5 mg;50 mg
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| Company Name: |
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
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| Tel: |
021-59167510 18117107507 |
| Email: |
vip@med-life.cn |
| Products Intro: |
Product Name:SNX-0723
CAS:1073969-18-2
Purity:>=99% Package:50mg;100mg;25mg;10mM*1mLinDMSO;10mg;5mg
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| | SNX-0723 Basic information |
| Product Name: | SNX-0723 | | Synonyms: | SNX-0723;Benzamide, 2-fluoro-6-[[(3S)-tetrahydro-3-furanyl]amino]-4-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indol-1-yl)- | | CAS: | 1073969-18-2 | | MF: | C22H26FN3O3 | | MW: | 399.46 | | EINECS: | | | Product Categories: | | | Mol File: | 1073969-18-2.mol |  |
| | SNX-0723 Chemical Properties |
| Boiling point | 568.5±50.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 20.83 mg/mL (52.15 mM; ultrasonic and warming and heat to 60°C) | | pka | 14.51±0.50(Predicted) |
| | SNX-0723 Usage And Synthesis |
| Biological Activity | SNX-0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX-0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX-0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM[1]. | | References | [1]. Dora Posfai, et al. Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01799-17. |
| | SNX-0723 Preparation Products And Raw materials |
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