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Isorhamnetin

Isorhamnetin Suppliers list
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:Isorhamnetin
CAS:480-19-3
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Isorhamnetin
CAS:480-19-3
Purity:HPLC>=98% Package:20mg
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Isorhamnetin
CAS:480-19-3
Purity:95% Package:100KG;480USD
Company Name: Chengdu GLP Biotech Co., Ltd
Tel: 13350802083
Email: scglp@glp-china.com
Products Intro: Product Name:Isorhamnetin
CAS:480-19-3
Purity:98% Package:1MG;1USD
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: 18080483897
Email: maggie@biopurify.com
Products Intro: Product Name:Isorhamnetin
CAS:480-19-3
Purity:98% HPLC Package:20mg;100mg;500mg;1g Remarks:BP0794

Lastest Price from Isorhamnetin manufacturers

  • Isorhamnetin 480-19-3
  • US $20.00 / mg
  • 2019-07-17
  • CAS:480-19-3
  • Min. Order: 20mg
  • Purity: ≥98%
  • Supply Ability: 1000.00 kgs
  • Isorhamnetin
  • US $480.00 / KG
  • 2019-07-06
  • CAS:480-19-3
  • Min. Order: 10KG
  • Purity: 95%
  • Supply Ability: 1000kg
Isorhamnetin Basic information
Description References
Product Name:Isorhamnetin
Synonyms:3’-methoxyquercetin;c.i.75680;isorhamnetol;ISOHAMNETIN:3'-METHOXY-3,4',5,7-TETRAHYDRO-XY-FLAVONE;3,5,7-trihydroxy-2-(4-hydroxy-3-methoxy-phenyl)chromen-4-one;QUERCETIN-3-METHYLETHER;QUERCETIN-3-ORTHO-METHYLETHER;ISORHAMNETIN hplc
CAS:480-19-3
MF:C16H12O7
MW:316.26
EINECS:207-545-5
Product Categories:Penta-substituted Flavones;Flavanols;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;-;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File:480-19-3.mol
Isorhamnetin Structure
Isorhamnetin Chemical Properties
Melting point 307°C
storage temp. 2-8°C
form neat
BRN 44723
InChIKeyIZQSVPBOUDKVDZ-UHFFFAOYSA-N
CAS DataBase Reference480-19-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-40
Safety Statements 22-36-26-36/37
WGK Germany 3
RTECS LK9275450
HS Code 29329990
MSDS Information
ProviderLanguage
SigmaAldrich English
Isorhamnetin Usage And Synthesis
DescriptionIsorhamnetin is a flavonoid, which occurs naturally in plants and it is also a metabolite of quercetin.
Isorhamnetin has anti-inflammatory effect as it can reduce the formation of large amounts of nitric oxide by the inhibition the activation of nuclear factor-κB (NF-κB), which is a significant transcription factor for inducible nitric oxide synthase.  Isorhamnetin is also reported to have effect in inducing the expression of neurofilaments, and it potentiated the NGF-induced neurite outgrowth and neurofilament expression, which could be a new direction in searching potential candidates as new drugs or food supplements for neurodegenerative diseases.
References[1] Mari Hämäläinen, Riina Nieminen, Pia Vuorela, Marina Heinonen and Eeva Moilanen, Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages, Mediators of Inflammation, 2007, vol. 2007, Article ID 45673
[2] Sherry L. Xu, Roy C. Y. Choi, Kevin Y. Zhu, Ka-Wing Leung, Ava J. Y. Guo, Dan Bi, Hong Xu, David T. W. Lau, Tina T. X. Dong and Karl W. K. Tsim, Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor, Evidence-Based Complementary and Alternative Medicine, 2012, vol. 2012, Article ID 278273
Chemical PropertiesBeige to lighet yellow powder
UsesA metabolite of the flavanoid Quercetin (Q509500) with antioxidant properties. It helps to protect H9c2 cardiomyoblasts against H2O2-induced oxidative stress via the modulation of PI3K/Akt and ERK1/2 signaling pathways.
UsesIsorhamnetin is a natural flavonol aglycone that is the 3-methyl metabolite of quercetin . It has antioxidant activity and inhibits xanthine oxidase (IC50 = 0.40 μM). Isorhamnetin also competitively inhibits the human multidrug and toxic compounds extrusion transporter 1 (Ki = 0.32 μM), which has an important role in the excretion of xenobiotics at the kidney and liver. It has also been reported to potentiate the neurological actions of nerve growth factor, diminish the cardiotoxic impact of doxorubicin, and have beneficial anti-cancer effects.
DefinitionChEBI: A monomethoxyflavone that is quercetin in which the hydroxy group at position 3' is replaced by a methoxy group.
Isorhamnetin Preparation Products And Raw materials
Tag:Isorhamnetin(480-19-3) Related Product Information
LARICITRIN-3,7,5'-TRI-O-GLUCOSIDE penta-O-ethylquercetin LARICITRIN-3,5'-DI-O-GLUCOSIDE 3,5,7-TRIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE 3,4-DIMETHOXY-3,5,7-TRIHYDROXYFLAVONE ARTEMETIN isorhamnetin3-beta-rutinosid QUERCETINPENTAACETATE CANNABISCITRIN 3'-BENZYLOXY-5,7-DIHYDROXY-3,4'-DIMETHOXYFLAVONE SYRINGETIN-3-GLUCOSIDE 3,7,3',4'-TETRAMETHYLGOSSYPETIN RHAMNAZIN SYRINGETIN Isorhamnetin 3-O-β-D-glucoside,Isorhamnetin 3-β-D-glucoside,Isorhamnetin-3-glucopyranoside,ISORHAMNETIN-3-O-GLUCOSIDE(P),ISORHAMNETIN-3-O-GLUCOSIDE HPLC 98%,ISORHAMNETIN-3-GLUCOSIDE,ISORHAMNETIN-3-O-GLUCOSIDE 3,3',4',5,6,7,8-heptamethoxyflavone Isorhamnetin 4'-Hydroxyacetophenone