| Company Name: |
Suzhou Xinkai Bio-Medical Technology Co., Ltd.
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| Tel: |
0512-67213637 13952409868 |
| Email: |
peter19zhang@163.com |
| Products Intro: |
Product Name:(S)-2-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-4-methylpenty((R)-1-amino-3-phenylpropyl)phosphinic acid
CAS:2007955-07-7
Purity:95%, ee98% Package:1 mg/200
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| Company Name: |
Shanghai Changyan Chem & Tech Co., Ltd.
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| Tel: |
021-20242659 18930833303 |
| Email: |
Sales@changyanchem.cn |
| Products Intro: |
Product Name:(S)-2-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-4-methylpenty((R)-1-amino-3-phenylpropyl)phosphinic acid
CAS:2007955-07-7
Package:100mg/;500mg/;1g/
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| Company Name: |
Nantong Hi-Future Biotechnology Co., Ltd
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| Tel: |
18051384581 |
| Email: |
sales@chemhifuture.com |
| Products Intro: |
Product Name:DG013A
CAS:2007955-07-7
Purity:98%HPLC Package:10mg，100mg，500mg，1g，2g，5g，10g，more
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| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:((S)-2-(((S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamoyl)-4-methylpentyl)((R)-1-amino-3-phenylpropyl)phosphinic acid
CAS:2007955-07-7
Purity:97% Package:1mg;5mg; Remarks:BD01183139
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:DG013A
CAS:2007955-07-7
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
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| | (S)-2-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-4-methylpenty((R)-1-amino-3-phenylpropyl)phosphinic acid Basic information |
| | (S)-2-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-4-methylpenty((R)-1-amino-3-phenylpropyl)phosphinic acid Chemical Properties |
| Boiling point | 888.8±65.0 °C(Predicted) | | density | 1.248±0.06 g/cm3(Predicted) | | pka | 2.17±0.50(Predicted) |
| | (S)-2-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-4-methylpenty((R)-1-amino-3-phenylpropyl)phosphinic acid Usage And Synthesis |
| Description | DG013A is a a phosphinic pseudotripeptide and ERAP2 inhibitor with nanomolar potency for ERAP2. A crystal structure of a phosphinic pseudotripeptide (DG013A) bound into the active site of ERAP2 revealed five distinct protein elements that were hypothesized to drive inhibitor potency. | | Uses | DG013A?is a phosphinic acid tripeptide mimetic inhibitor. DG013A displays significantly weak affinity for both ERAP1 (IC50=33?nM)?and ERAP2 (IC50=11?nM). DG013A can be used for the research of autoimmune disease and cancer[1]. | | References | [1] Birgit Wilding,?et al. Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1. Bioorg Med Chem Lett.?2021 Jun 15;42:128050. DOI:10.1016/j.bmcl.2021.128050 |
| | (S)-2-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-4-methylpenty((R)-1-amino-3-phenylpropyl)phosphinic acid Preparation Products And Raw materials |
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