| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-dimethyl Histone H3 (Arg2), symmetric Antibody
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Product Name:Anti-dimethyl Histone H3 (Arg2), symmetric Antibody
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| | Anti-dimethyl Histone H3 (Arg2), symmetric Antibody Basic information |
| | Anti-dimethyl Histone H3 (Arg2), symmetric Antibody Chemical Properties |
| | Anti-dimethyl Histone H3 (Arg2), symmetric Antibody Usage And Synthesis |
| Uses | This Anti-dimethyl Histone H3 (Arg2) antibody, symmetric is validated for use in western blotting, dot blot, IHC & ChIP for the detection of dimethyl Histone H3 (Arg2). | | General Description | Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histones are modified post-translationally by the actions of enzymes in both the nucleus and cytoplasm. These modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). The modifications occur predominantly on the N-terminal and C-terminal tails that extend beyond the nucleosome core particle. |
| | Anti-dimethyl Histone H3 (Arg2), symmetric Antibody Preparation Products And Raw materials |
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