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β-Secretase Substrate IV, Fluorogenic - Calbiochem

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Products Intro: Product Name:β-Secretase Substrate IV, Fluorogenic - Calbiochem
β-Secretase Substrate IV, Fluorogenic - Calbiochem Basic information
Product Name:β-Secretase Substrate IV, Fluorogenic - Calbiochem
Synonyms:β-Secretase Substrate IV, Fluorogenic - Calbiochem
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MW:0
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Mol File:Mol File
β-Secretase Substrate IV, Fluorogenic - Calbiochem Structure
β-Secretase Substrate IV, Fluorogenic - Calbiochem Chemical Properties
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MSDS Information
β-Secretase Substrate IV, Fluorogenic - Calbiochem Usage And Synthesis
General DescriptionA highly sensitive fluorescence resonance energy transfer (FRET) peptide substrate (excitation max.: ~350 nm; emission max.: ~490), based on the GVNLDAEF sequence derived from the β-secretase site of the Swedish mutation of Amyloid Precursor Protein. Hydrolysis of the substrate at Leu-Asp bond by β-secretase results in fluorescence enhancement. Reported Kcat/km values (min-1/μM) for pro-mempasin 2 and its proteolytically activated species Leu28p-mempasin 2 are 0.044 and 0.040, respectively (at pH 4.5, 37°C).
Biochem/physiol ActionsProduct does not compete with ATP.
β-Secretase Substrate IV, Fluorogenic - Calbiochem Preparation Products And Raw materials
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