N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

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Products Intro: Product Name:N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
CAS:2183440-74-4
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
CAS:2183440-74-4
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
CAS:2183440-74-4
Package:5mg;165USD|2mg;98USD
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Products Intro: Product Name:N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
CAS:2183440-74-4
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Xian confluore Biological Technology Co., Ltd.
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Products Intro: Product Name:N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
CAS:2183440-74-4
Purity:>95.00% Package:100mg

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid manufacturers

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid Basic information
Product Name:N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
Synonyms:N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
CAS:2183440-74-4
MF:C29H55N5O13
MW:681.78
EINECS:
Product Categories:
Mol File:2183440-74-4.mol
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid Structure
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid Chemical Properties
storage temp. Storage temp. 2-8°C
solubility Soluble in Water, DMSO, DCM, DMF
form Viscous Liquid
color Colorless to light yellow
Safety Information
MSDS Information
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid Usage And Synthesis
DescriptionN-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent. The azide (N3) group participates in Click Chemistry reactions with alkynes, DBCO and BCN. The terminal carboxylic acid can react with primary amine groups. The Boc protection can be removed under acidic conditions.
UsesN-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid Preparation Products And Raw materials
Tag:N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid(2183440-74-4) Related Product Information

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