- RIMEXOLONE (100 MG)
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- $0.00 / 1kg
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2024-04-02
- CAS:49697-38-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20tons
- RIMEXOLONE
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- $1000.00 / 1KG
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2019-07-06
- CAS:49697-38-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: Customized
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| RIMEXOLONE (100 MG) Basic information |
Product Name: | RIMEXOLONE (100 MG) | Synonyms: | (11β,16α,17β)-;(17S)-11β-Hydroxy-16α,17α-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one;11β-Hydroxy-16α,17α-dimethyl-17β-propionylandrosta-1,4-dien-3-one;Org-6216;(11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one;RIMEXOLONE (100 MG);Rimexolone;(11β, 16α, 17β)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androstra-1,4-dien-3-one | CAS: | 49697-38-3 | MF: | C24H34O3 | MW: | 370.53 | EINECS: | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids | Mol File: | 49697-38-3.mol | |
| RIMEXOLONE (100 MG) Chemical Properties |
Melting point | 258-268 ºC | alpha | D +100° (c = 0.92 in pyridine) | Boiling point | 507.0±50.0 °C(Predicted) | density | 1.12 | pka | 14.42±0.70(Predicted) | InChIKey | QTTRZHGPGKRAFB-OOKHYKNYSA-N |
| RIMEXOLONE (100 MG) Usage And Synthesis |
Description | Rimexolone, an ophthalmic corticosteroid, was launched in 1995 in the U.S.A. for
the treatment of postoperative inflammation following ocular surgery and anterior
uveitis. Rimexolone has high corticoid receptor affinity and is a potent local
antiinflammatory agent with minimal systemic effects and virtually no atrophogenic
action in many animal models studied, unique among a wide range of topical steroids.
Rapid onset, long duration of action plus a superior safety profile are characteristics of
rimexolone. It was also approved in Europe for the treatment of rheumatoid arthritis and
is currently in clinical trials for tendinitis and osteoarthritis. | Originator | Akzo (Netherlands) | Uses | Anti-inflammatory (local). | Definition | ChEBI: Rimexolone is a 20-oxo steroid. | Brand name | Vexol (Alcon). | General Description | Rimexolone, 11β-hydroxy-16α,17α-dimethyl-17-(1-oxopropyl)androsta-1,4-diene-3-one,like medrysone and fluorometholone, lacks the C21 OHgroup. In addition, rimexolone has an additional methylgroup in the 17 -position, a site where an OH group is typicallyfound. Rimexolone is available as a suspension forophthalmic use. |
| RIMEXOLONE (100 MG) Preparation Products And Raw materials |
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