TOPOTECAN-D6

TOPOTECAN-D6 Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:Topotecan-d6
CAS:1044904-10-0
Package:10Mg,1Mg
Company Name: Chemsky(shanghai)International Co.,Ltd.  
Tel: 021-50135380
Email: shchemsky@sina.com
Products Intro: Product Name:Topotecan-d6
CAS:1044904-10-0
Purity:98%
Company Name: Shenzhen Regent Biochemical Technology Co., Ltd.  
Tel: 0755-85201366 18938635012
Email: sales@regentsciences.com
Products Intro: Product Name:Topotecan-d6
CAS:1044904-10-0
Purity:98% Package:1mg
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774
Email: sales@glpbio.cn
Products Intro: Product Name:Topotecan-d6
CAS:1044904-10-0
Purity:>98% Package:1mg;10mg;50mg;100mg;
Company Name: Shenzhen Polymeri Biochemical Technology Co., Ltd.  
Tel: +86-400-002-6226 +86-13028896684
Email: sales@rrkchem.com
Products Intro: Product Name:Topotecan-d6
CAS:1044904-10-0
TOPOTECAN-D6 Basic information
Product Name:TOPOTECAN-D6
Synonyms:TOPOTECAN-D6;(4S)-10-[[Di(methyl-d3)amino]methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[346-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;SKF-104864A-d6;(4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3’,4’,6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Hycamtin-d6;NSC-609669-d6;(4S)-10-[[Di(methyl-d3)amino]methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;[2H6]-Topotecan
CAS:1044904-10-0
MF:C23H23N3O5
MW:421.45
EINECS:
Product Categories:Heterocycles;Isotope Labelled Compounds;Inhibitors;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals
Mol File:1044904-10-0.mol
TOPOTECAN-D6 Structure
TOPOTECAN-D6 Chemical Properties
Melting point 213-218°C (dec)
storage temp. -20°C Freezer
CAS DataBase Reference1044904-10-0
Safety Information
MSDS Information
TOPOTECAN-D6 Usage And Synthesis
DescriptionTopotecan-d6 is intended for use as an internal standard for the quantification of topotecan by GC- or LC-MS. Topotecan is an inhibitor of DNA topoisomerase I and a derivative of the DNA topoisomerase I inhibitor camptothecin . Topotecan inhibits DNA topoisomerase I in human MCF-7 breast and DU145 prostate cancer cells with IC50 values of 13 and 2 nM, respectively, in a cell-based luciferase reporter assay. Topotecan induces cytotoxicity and DNA damage in HT-29 human colon adenocarcinoma cells (IC50s = 33 and 280 nM, respectively). Formulations containing topotecan have been used in the treatment of small-cell lung cancer.
Chemical PropertiesLight Yellow to Greenish Powder
UsesLabelled Topotecan (T542500). A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic.
UsesLabelled Topotecan. A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic
TOPOTECAN-D6 Preparation Products And Raw materials
Tag:TOPOTECAN-D6(1044904-10-0) Related Product Information
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