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Human Menopausal Gonadotrophin

Human Menopausal Gonadotrophin Suppliers list
Company Name: Wuhan Xinhao Biotechnology Co., Ltd
Tel: +86-18120578002 +86-18120578002
Email: xinhao-6@xinhaoshengwu.com
Products Intro: Product Name:HMG HUMAN MENOPAUSAL GONADOTROPHIN
CAS:61489-71-2
Purity:99% Package:1kg;10USD|5kg;50USD|25kg;100USD
Company Name: Shanghai Aosiris new Material Technology Co., LTD
Tel: +8617513190836
Email: wrjmoon2000@163.com
Products Intro: Product Name:HMG
CAS:61489-71-2
Purity:99.9% Package:1kg;3USD|5kg;2USD|10kg;1USD
Company Name: Nantong Guangyuan Chemicl Co,Ltd
Tel: +undefined17712220823
Email: admin@guyunchem.com
Products Intro: Product Name:HMG
CAS:61489-71-2
Purity:99% Package:1kg;10USD
Company Name: Sigma Audley
Tel: +86-18336680971 +86-18126314766
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Products Intro: Product Name:HMG
CAS:61489-71-2
Purity:99.9% Package:1box;25USD|20box;20USD|50box;15USD
Company Name: Hebei Kangcang new material Technology Co., LTD
Tel: +8619133911216
Email: Jany1001@kangcang.com.cn
Products Intro: Product Name:HMG
CAS:61489-71-2
Purity:99% Package:1box;80USD|10box;70USD|100box;60USD

Human Menopausal Gonadotrophin manufacturers

  • HMG
  • HMG pictures
  • $100.00 / 1kg
  • 2024-03-28
  • CAS:61489-71-2
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 20ton
  • HMG
  • HMG pictures
  • $80.00/ box
  • 2024-03-28
  • CAS:61489-71-2
  • Min. Order: 1box
  • Purity: 99%
  • Supply Ability: 100000kg
  • HMG
  • HMG pictures
  • $0.00 / 1G
  • 2024-03-28
  • CAS:61489-71-2
  • Min. Order: 1G
  • Purity: 99%
  • Supply Ability: 5kg
Human Menopausal Gonadotrophin Basic information
Product Name:Human Menopausal Gonadotrophin
Synonyms:MENOPAUSAL GONADOTROPHIN, HUMAN URINE;hMG Fuji;Humegon 100;Lepori;Menogon;Menogon HP;Menopur;Merional
CAS:61489-71-2
MF:C9H18O
MW:142.23862
EINECS:
Product Categories:Peptides
Mol File:61489-71-2.mol
Human Menopausal Gonadotrophin Structure
Human Menopausal Gonadotrophin Chemical Properties
storage temp. 2-8°C
InChIInChI=1S/C9H18O/c1-9(2,3)7-5-4-6-8-10/h8H,4-7H2,1-3H3
InChIKeyCBUWTGCATVNMJE-UHFFFAOYSA-N
SMILESC(=O)CCCCC(C)(C)C
CAS DataBase Reference61489-71-2(CAS DataBase Reference)
EPA Substance Registry SystemMenotropins (61489-71-2)
Safety Information
Hazard Codes B
WGK Germany 3
RTECS MT6425640
MSDS Information
ProviderLanguage
SigmaAldrich English
Human Menopausal Gonadotrophin Usage And Synthesis
UsesGonad-stimulating principle.
UsesGonadotropin from human menopausal urine has been used as a supplement in pre-incubated maturation medium for the culture of bovine cumulus oocyte complexes (COCs) to study the effects of multiple freeze-thawing of bovine epididymal sperm on in vitro development of embryo.
Brand nameHumegon (Organon); Pergonal (Serono).
General DescriptionPituitary hormones prepared from the urine of postmenopausalwomen whose ovarian tissue does not respondto gonadotropin are available for medicinal use as theproduct menotropins (Pergonal). The latter has FSH andLH gonadotropin activity in a 1:1 ratio. Menotropins areuseful in the treatment of anovular women whose ovariesrespond to pituitary gonadotropins but who have a gonadotropindeficiency caused by either pituitary or hypothalamusmalfunction. Usually, menotropins are administeredintramuscularly in an initial dose of 75 IU of FSHand 75 IU of LH daily for 9 to 12 days, followed by 10,000IU of chorionic gonadotropin 1 day after the last dose ofmenotropins.
Biochem/physiol ActionsGonadotropin interacts with members of the GPCR (G-protein coupled receptor family), and upon activation they induce adenylyl cyclase. This hormone is synthesized in male reproductive tract and has high concentration in semen, especially the a subunit. This subunit is linked with spermatogenesis, and lower levels are present in males with aberrant semen quality.
Clinical UseMenotropins are a natural product that is obtained from the urine of postmenopausal women and then biologically standardized (international units [IU]) for FSH and LH activities in an approximate ratio of 1:1. Menotropins are used in males with primary (hypothalamic) or secondary (pituitary) hypogonadism to stimulate spermatogenesis, providing they have been treated previously with human chorionic gonadotropin (hCG; a peptide hormone of placental origin that has activity very similar to LH) to effect masculinization (increased testosterone inducing ovulation in women who are having difficulty ovulating as a result of either hypothalamic or pituitary hormonal dysfunction. The menotropins are given for 7 to 12 days, and after clinical evaluation (via ultrasound) indicates the presence of a mature follicle, a single dose of hCG is given to simulate the typical LH surge that normally triggers ovulation. Also, women use the combination of menotropins and hCG to promote the development of multiple follicles when they are participating in an IVF program requiring the recruitment of follicles.
Side effects Side effects: Headache, mild stomach pain/bloating, redness/pain at the injection site, breast tenderness, or dizziness may occur.
Serious side effects, including: vaginal bleeding, flu-like symptoms (such as fever, chills, joint pain, muscle ache, tiredness).
Human Menopausal Gonadotrophin Preparation Products And Raw materials
Tag:Human Menopausal Gonadotrophin(61489-71-2) Related Product Information
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