- Concanavalin A
-
- $0.00 / 1KG
-
2023-09-06
- CAS:11028-71-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
- Concanavalin A
-
- $0.00 / 1KG
-
2023-09-06
- CAS:11028-71-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
|
| | Concanavalin A Basic information |
| Product Name: | Concanavalin A | | Synonyms: | LECTIN FROM CANAVALIA ENSIFORMISTYPE IV- S GAMMA-IR;LECTIN CONCANAVALIN A FROM CANAVALIAENSI FORMIS FER;CONCANAVALIN A FROM CANAVALIAENSIFORMIS TYPE V;LECTIN FROM CONCANAVALIN A PEROXIDASE*LA BELED;LECTIN FROM CONCANAVALIN A TYPE VI;CONCANAVALIN A (CON A);concanavalin a from canavalia ensiformis (jack bean);CONCANAVALIN | | CAS: | 11028-71-0 | | MF: | C15H24 | | MW: | 0 | | EINECS: | 234-258-2 | | Product Categories: | reagent | | Mol File: | Mol File | ![Concanavalin A Structure]() |
| | Concanavalin A Chemical Properties |
| Fp | 39 °C | | storage temp. | -20°C | | solubility | PBS: 5 mg/mL, slightly hazy | | form | powder | | Water Solubility | Slightly soluble in water and phosfate buffered saline. | | CAS DataBase Reference | 11028-71-0 |
| | Concanavalin A Usage And Synthesis |
| Chemical Properties | Lyophilized | | Uses | Concanavalin A is a plant lectin that is a T-cell mitogen, and induces apoptosis in human fibroblasts. | | Uses | Concanavalin A is a unique lectin purified from the jack bean, C. ensiformis, that selectively cross-links cell-surface glycoproteins and affects the initiation of cell agglutination, mitogenesis, and apoptosis. Concanavalin A specifically binds to α-mannose and α-galactose structures found in sugars, glycoproteins, and glycolipids and has been used in affinity chromatography purifications of various glycoproteins and cellular structures. At 20 mg/kg concanavalin A is also used to induce liver injury in experimental mouse models of autoimmune hepatitis in order to study immune regulation by macrophages and T cells. Concanavalin A is toxic to several tumor cell lines and has been reported to induce programmed cell death of cortical neurons by a mechanism similar to that of the amyloid β peptide. | | Uses | As a reagent in analytical and preparative biochemistry; as a probe in studies of cell surface membrane dynamics and cell division. | | Definition | A lectin mitogen that binds specifically to and agglutinates transforms into tumors. It binds to glucose
and mannose residues in the surface. | | General Description | Concanavalin A is a protein containing only β-sheets in its structure, and belongs to the legume lectins family. | | Hazard | Poison; teratogen; mutagen. | | Biochem/physiol Actions | Concanavalin A is known to stimulate acute hepatic inflammation and acts as a T‐cell mitogen. It has inhibitory effect on hepatocellular carcinoma by inducing autophagy. | | storage | -20°C |
| | Concanavalin A Preparation Products And Raw materials |
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