- Sodium dichloroacetate
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- $8.00 / 1KG
-
2024-04-09
- CAS:2156-56-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- Sodium dichloroacetate
-
- $0.00 / 1KG
-
2023-09-06
- CAS:2156-56-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
- Sodium dichloroacetate
-
- $25.00 / 1KG
-
2023-09-04
- CAS:2156-56-1
- Min. Order: 1KG
- Purity: 0.99
- Supply Ability: 20MT/MON
Related articles - What is Sodium dichloroacetate?
- Sodium Dichloroacetate is the sodium salt of dichloroacetic acid with potential antineoplastic activity. Dichloroacetate ion i....
- Dec 30，2019
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| | Sodium dichloroacetate Basic information | | Uses |
| Product Name: | Sodium dichloroacetate | | Synonyms: | dichloroacetate,sodiumsalt;dichloro-aceticacisodiumsalt;Sodiumdichloracetate;NATRIUMDICHLORACETAT;SODIUM DICHLOROACETATE;DICHLOROACETIC ACID SODIUM SALT;Sodiumdichloroacetate,97%;SODIUM DICHLOROACETIC ACID | | CAS: | 2156-56-1 | | MF: | C2H3Cl2NaO2 | | MW: | 152.93 | | EINECS: | 218-461-3 | | Product Categories: | | | Mol File: | 2156-56-1.mol |  |
| | Sodium dichloroacetate Chemical Properties |
| Melting point | 198 °C (dec.) (lit.) | | storage temp. | Inert atmosphere,2-8°C | | solubility | Methanol (Slightly), Water (Slightly) | | form | Powder | | color | White | | PH | 6.0 to 8.5(50g/L, 25 ℃) | | Water Solubility | soluble in cold water | | Sensitive | Moisture Sensitive | | Stability: | Hygroscopic | | InChIKey | LUPNKHXLFSSUGS-UHFFFAOYSA-M | | CAS DataBase Reference | 2156-56-1(CAS DataBase Reference) | | EPA Substance Registry System | Sodium dichloroacetate (2156-56-1) |
| | Sodium dichloroacetate Usage And Synthesis |
| Uses | Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and is an orally absorbable small molecular compound for MELAS syndrome, and children with congenital lactic acidosis and other diseases that are treated in the clinic. Recent studies had found that DCA acts as a potential vasoprotective agent by inhibiting PDK2 and reducing coronary endarterium proliferation. Further, DCA promotes brain regeneration after cerebral ischemia, which indicates that DCA might play an important role in VD.
| | Chemical Properties | white powder | | Uses | Sodium dichloroacetate is an inhibitor of mitochondrial pyruvate dehydrogenase kinase. | | Uses | Treatment of neurologic injury (pyruvate dehydrogenase activator). | | Brand name | Ceresine (Cypros). | | General Description | Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity. | | Biological Activity | Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo . | | storage | Desiccate at RT |
| | Sodium dichloroacetate Preparation Products And Raw materials |
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