Related articles - The toxic effects of Brusatol
- Brusatol is a natural quassinoid that shows a potential therapeutic use in cancer models by the inhibition of Nuclear factor e....
- Sep 19，2019
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| Product Name: | BRUSATOL | | Synonyms: | BRUSATOL;Regaloside B;β-D-Glucopyranoside, (1S)-2-(acetyloxy)-1-[[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]methyl]ethyl;b-D-Glucopyranoside,2-(acetyloxy)-1-[[[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]methyl]ethyl,[S-(E)]- | | CAS: | 114420-67-6 | | MF: | C20H26O11 | | MW: | 442.41 | | EINECS: | | | Product Categories: | | | Mol File: | 114420-67-6.mol |  |
| | BRUSATOL Chemical Properties |
| Boiling point | 727.5±60.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 8.58±0.15(Predicted) | | CAS DataBase Reference | 114420-67-6 |
| | BRUSATOL Usage And Synthesis |
| Description | Brusatol is a natural quassinoid that shows a potential therapeutic use in cancer models by the inhibition of Nuclear factor erythroid 2-related factor 2 (Nrf2) and is capable of inducing a variety of biological effects. The effects of Brusatol on oocyte meiosis has not been addressed. | | Uses | Clinically, the research shows brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism, and it provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity. Brusatol overcomes chemoresistance through inhibition of protein translation. |
| | BRUSATOL Preparation Products And Raw materials |
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