| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
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| Tel: |
010-60605840 15801484223; |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:Calcitriol Derivatives
CAS:2070009-24-2
Package:1mg;5mg Remarks: 试剂级
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| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.com |
| Products Intro: |
Product Name:Calcitriol Derivatives
CAS:2070009-24-2
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| | INDEX NAME NOT YET ASSIGNED Basic information |
| | INDEX NAME NOT YET ASSIGNED Chemical Properties |
| Boiling point | 629.7±55.0 °C(Predicted) | | density | 1.06±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 14.31±0.40(Predicted) | | color | White to off-white |
| | INDEX NAME NOT YET ASSIGNED Usage And Synthesis |
| Uses | Calcitriol Derivatives is a vitamin D3 analog. v | | References | [1] Barrera D, Noyola-Martínez N, Avila E, Halhali A, Larrea F, Díaz L. Calcitriol inhibits interleukin-10 expression in cultured human trophoblasts under normal and inflammatory conditions. Cytokine. 2012 Mar;57(3):316-21. DOI:10.1016/j.cyto.2011.11.020
[2] Lydia A, Asanuma K, Nonaka K, Takagi M, Jeong KH, Kodama F, Asao R, Asanuma E, Prodjosudjadi W, Tomino Y. Effects of 22-oxa-calcitriol on podocyte injury in adriamycin-induced nephrosis. Am J Nephrol. 2012;35(1):58-68. DOI:10.1159/000334626
[3] Michalak K, Wicha J. Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione. J Org Chem. 2011 Aug 19;76(16):6906-11. DOI:10.1021/jo201083w
[4] Moorthi RN, Kandula P, Moe SM. Optimal vitamin D, calcitriol, and vitamin D analog replacement in chronic kidney disease: to D or not to D: that is the question. Curr Opin Nephrol Hypertens. 2011 Jul;20(4):354-9. DOI:10.1097/MNH.0b013e3283470450
[5] Yu WD, Ma Y, Flynn G, Muindi JR, Kong RX, Trump DL, Johnson CS. Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system. Cell Cycle. 2010 Aug 1;9(15):3022-9. DOI:10.4161/cc.9.15.12381 |
| | INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials |
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