| Company Name: |
Aikon International Limited
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| Tel: |
025-66113011 18112977050 |
| Email: |
cb6@aikonchem.com |
| Products Intro: |
Product Name:(2-Hydroxycyclohexane-1,1,3,3-tetrayl)tetrakis(methylene) tetranicotinate
CAS:27959-26-8
Purity:95% HPLC or GC Package:10G,5G;1G
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| | Nicomol Basic information |
| Product Name: | Nicomol | | Synonyms: | [2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl pyridine-3-carboxylate;nicomol;2,2,6,6-Tetrakis(nicotinoyloxymethyl)cyclohexanol;2-Hydroxy-1,1,3,3-cyclohexanetetramethanol 1,1,3,3-tetranicotinate;Atomirate;Cholexamin;K-31;[2-hydroxy-1,3,3-tris(pyridin-3-ylcarbonyloxymethyl)cyclohexyl]methyl pyridine-3-carboxylate | | CAS: | 27959-26-8 | | MF: | C34H32N4O9 | | MW: | 640.63928 | | EINECS: | 2487489 | | Product Categories: | | | Mol File: | 27959-26-8.mol |  |
| | Nicomol Chemical Properties |
| Melting point | 177-180° | | Boiling point | 672.42°C (rough estimate) | | density | 1.3015 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | 2-8°C | | pka | 13.53±0.60(Predicted) |
| Toxicity | LD50 in mice, male and female rats (g/kg): >10, 15, <10 orally; >5, >2.5, >2.5 i.p. (Sugawara) |
| | Nicomol Usage And Synthesis |
| Originator | Cholexamine,Kyorin,Japan,1971 | | Definition | ChEBI: Nicomol is an organic molecular entity. | | Manufacturing Process | To a mixture of 60 cc of benzene, 40 cc of pyridine and 17 g of hydrochloric
acid salt of nicotinic acid chloride, was added 4.5 g of 2,2,6,6-
tetramethylolcyclohexanol, and the whole mixture was refuxed at 75°C to
80°C for 2.5 hours. After the mixture was cooled water was added. Precipitate
formed was separated by filtration, washed thoroughly with water and dried.
Recrystallization from dilute acetic acid gave 14 g of the final compound,
melting point 177°C to 180°C. | | Therapeutic Function | Anticholesteremic |
| | Nicomol Preparation Products And Raw materials |
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