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Olean-12-ene-3,16,21,22,23,28-hexol, 21-[(2E)-2-methyl-2-butenoate], (3β,4β,16α,21β,22α)- Suppliers list
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Product Name:Protoescigenin 21-tiglate
CAS:7047-43-0
Purity:HPLC≥98% Package:5mg；10mg；20mg；50mg；100mg；200mg
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| | Olean-12-ene-3,16,21,22,23,28-hexol, 21-[(2E)-2-methyl-2-butenoate], (3β,4β,16α,21β,22α)- Basic information |
| Product Name: | Olean-12-ene-3,16,21,22,23,28-hexol, 21-[(2E)-2-methyl-2-butenoate], (3β,4β,16α,21β,22α)- | | Synonyms: | Olean-12-ene-3,16,21,22,23,28-hexol, 21-[(2E)-2-methyl-2-butenoate], (3β,4β,16α,21β,22α)-;Protoescigenin 21-tiglate | | CAS: | 7047-43-0 | | MF: | C35H56O7 | | MW: | 588.83 | | EINECS: | | | Product Categories: | | | Mol File: | 7047-43-0.mol | ![Olean-12-ene-3,16,21,22,23,28-hexol, 21-[(2E)-2-methyl-2-butenoate], (3β,4β,16α,21β,22α)- Structure](CAS/20211123/GIF/7047-43-0.gif) |
| | Olean-12-ene-3,16,21,22,23,28-hexol, 21-[(2E)-2-methyl-2-butenoate], (3β,4β,16α,21β,22α)- Chemical Properties |
| Boiling point | 687.0±55.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | pka | 13.51±0.70(Predicted) |
| | Olean-12-ene-3,16,21,22,23,28-hexol, 21-[(2E)-2-methyl-2-butenoate], (3β,4β,16α,21β,22α)- Usage And Synthesis |
| Uses | Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively[1]. | | References | [1] Yang Y, et al. 16-Tigloyl linked barrigenol-like triterpenoid from Semen Aesculi and its anti-tumor activity in vivo and in vitro[J]. RSC advances, 2019, 9(54): 31758-31772. |
| | Olean-12-ene-3,16,21,22,23,28-hexol, 21-[(2E)-2-methyl-2-butenoate], (3β,4β,16α,21β,22α)- Preparation Products And Raw materials |
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