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Mecobalamin

Mecobalamin Suppliers list
Company Name: Xi'an MC Biotech, Co., Ltd.
Tel: 02989275612
Email: mcbio_sales@163.com
Products Intro: Product Name:Mecobalamin
Package:1g,5g,25g,100g,500g1000g
Company Name: Guangzhou Sunton Biotechnology Co., Ltd.
Tel: 18575736215
Email: sunton01@sunton88.com
Products Intro: Product Name:Vitamin B12
CAS:13422-55-4
Purity:99% Package:10kg 25kg 50 kilograms per barrel
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:13422-55-4
CAS:13422-55-4
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008615858145714
Email: fandachem@gmail.com
Products Intro: Product Name:Methylcobalamine (vitamin b12, Mecobalamin) USP grade
CAS:13422-55-4
Purity:as customers' requirements Package:as in COA
Company Name: Nanjing ChemLin Chemical Industry Co., Ltd.
Tel: 025-83697070;product@chemlin.com.cn
Email: product@chemlin.com.cn
Products Intro: CAS:13422-55-4
Purity:98% Package:g-Kg Remarks:Dark red crystal or crystalline powder

Lastest Price from Mecobalamin manufacturers

  • Mecobalamin
  • US $0.00-0.00 / Kg/Bag
  • 2021-09-29
  • CAS:13422-55-4
  • Min. Order: 100g
  • Purity: 98.0%-101.0%; CP
  • Supply Ability: 10kg
  • Vitamin B12
  • US $0.00 / Kg/Drum
  • 2021-09-07
  • CAS:13422-55-4
  • Min. Order: 1KG
  • Purity: 99.9%
  • Supply Ability: 100000kg per month
  • Methylcobalamin
  • US $10.00 / Kg/Drum
  • 2021-08-26
  • CAS:13422-55-4
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 10 ton

Related articles

  • Pharmacology of Methylcobalamin
  • Methylcobalamin is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lac....
  • Nov 12,2019
Mecobalamin Basic information
Pharmacological action Uses
Product Name:Mecobalamin
Synonyms:MECOBALAMIN;MECOBALAMINE;METHYLCOBALAMIN;cobalt-methylcobalamin;cobinamide,cobalt-methylderivative,hydroxide,dihydrogenphosphate(ester),;Methyl-5,6-dimethylbenzimidazolylcobalamin;Vitamin B12;Algobaz
CAS:13422-55-4
MF:C63H91CoN13O14P
MW:1344.38
EINECS:236-535-3
Product Categories:API;Pharmaceutical intermediates;PHARMACEUTICALS;Nutritional Supplements;Intermediates & Fine Chemicals;Vitamin B12;Nutrition Research;Vitamins;Vitamin Ingredients
Mol File:13422-55-4.mol
Mecobalamin Structure
Mecobalamin Chemical Properties
Melting point >190°C (dec.)
storage temp. Sealed in dry,Store in freezer, under -20°C
pkapK1:7.64(+1) (25°C)
Water Solubility Partially soluble in cold water, hot water.
InChIKeyJEWJRMKHSMTXPP-WYVZQNDMSA-L
CAS DataBase Reference13422-55-4
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25-36-26
WGK Germany 2
RTECS GG3745000
HS Code 29362600
ToxicityLD50 oral in rat: > 5gm/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
Mecobalamin Usage And Synthesis
Pharmacological actionMecobalamin as vitamin B12 derivatives, should be called "methyl vitamin B12" according to the chemical structure of name, the functional groups of methylation can be involved in the biochemical process of methyl transfer activity, promoting to nucleic acid of nerve tissue, the metabolism of protein and fat, , can stimulate the synthesis of lecithin Schwann cells, repairing the damaged myelin, improving nerve conduction velocity; directly into nerve cells, and stimulating axon regeneration of damaged area; stimulating protein synthesis in nerve cells and enhanced synthetic metabolism of axons to prevent axonal degeneration; involved in nucleic acid synthesis, promoted hematopoietic function. The treatment is clinically used in diabetic neuropathy, long-term use of macrovascular complications of diabetes are the curative effect.
Mecobalamin is used for peripheral nerve disorders treatment drug, compared with other vitamin B12 preparations, having good transfer on the nervous tissue, through the methyl transfer reaction, can promote nucleic acid, protein lipid metabolism, repairing the damaged nerve tissue. In homocysteine synthetic egg ammonia acid process, it plays a role of coenzyme, especially by deoxyuridine synthesis of thymidine, promoting DNA and RNA synthesis of participation. Also in the experiment of glial cells, the drugs can improve methionine synthase activity and promote the synthesis of myelin lipids lecithin. Improving the nerve tissue metabolism, can promot axis cable and protein synthesis, make the delivery rate of the skeletal protein close to normal, maintain axonal functions. Besides mecobalamin injections can inhibit nerve tissue of abnormal impulse conduction, promoting redl blood cells mature, split, improving anemia. Mecobalamin can be quickly restored due to lack of B12 and reduce the number of rat erythrocytes, hemoglobin, hematocrit value. Used for megaloblastic red blood cell anemia and peripheral nerve disorder due to the lack of vitamin B12.
The above information is edited by the Chemicalbook Hanya.
Uses1.It is used for the treatment of nervous system diseases, relieving pain and numbness, speeded relieving pain, improving pain caused by cervical spondylosis, treatment of sudden deafness, etc.
2.Methylcobalamin is a kind of endogenous coenzyme B12, participating in the one carbon unit cycle, playing an important role in the synthesis of methionine homocysteine methyl transfer reaction process.
Chemical PropertiesDark Red Crystalline Powder
Physical propertiesVitamin B12 is an octahedral cobalt complex consisting of a porphyrin-like, cobalt centered macroring (called a corrin ring or nucleus). The corrinoids are red, red orange, or yellow crystalline substances that show intense absorption spectra above 300 nm owing to the π–π transitions of the corrin nucleus. They are soluble in water and are fairly stable to heat but decompose at temperatures above ~210 °C without melting.
Vitamin B12 reacts with ascorbic acid, resulting in the reduction and subsequent degradation of the former, which releases its cobalt atom as the free ion. Cobalamins are more stable in the presence of ascorbic acid but unstable to light
UsesOne of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic).
Uses?Histamine receptor, Alzheimer research
DefinitionA vitamin B 12 analog used as an intermediate in the synthesis of methane. It is responsible for the methylation of inorganic mercury by anaerobic bacteria in bottom sediments. Through the action of methylcobalamin in an anaerobic bacteria in bottom sediments of aquatic systems, arsenic(III) is methylated to methanearsonic acid then to cacodylic acid.
Mecobalamin Preparation Products And Raw materials
Raw materialsVitamin B12
Tag:Mecobalamin(13422-55-4) Related Product Information
HYDROXOCOBALAMIN VITAMIN B12,VITAMIN B12A,VITAMIN B12B,VITAMIN B12A HYDROCHLORIDE VITAMIN B12A ACETATE SALT,VITAMIN B12A ACETATE Thiamine chloride Vitamin A palmitate Retinyl acetate Vitamin B12 VITAMIN B12 DEFICIENT DIET, MODIFIED MECOBALAMINE 2,4,6-TRIMETHYL-3-HEPTENE 1-AMINO-10-UNDECENE cobinamide 5,6-Dimethylbenzimidazole 1,12-Dodecanediamine CYANOCOBALAMIN (VITAMIN B12) USP(CRM STANDARD) Mecobalamin MULTIVITAMIN Methyl Vitamin AD3