Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:RYL-552;RYL 552,RYL552 CAS:1801444-56-3 Purity:98% Package:25 mg
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| 4(1H)-Quinolinone, 5-fluoro-3-methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methyl]phenyl]- Basic information |
| 4(1H)-Quinolinone, 5-fluoro-3-methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methyl]phenyl]- Chemical Properties |
Boiling point | 496.3±45.0 °C(Predicted) | density | 1.309±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | pka | 0.77±0.70(Predicted) |
| 4(1H)-Quinolinone, 5-fluoro-3-methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methyl]phenyl]- Usage And Synthesis |
Biological Activity | RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor[1]. | References | [1]. Kristin D Lane, et al. Selection of Plasmodium falciparum cytochrome B mutants by putative PfNDH2 inhibitors. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6285-6290. |
| 4(1H)-Quinolinone, 5-fluoro-3-methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methyl]phenyl]- Preparation Products And Raw materials |
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