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Sulfamethoxypyridazine

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Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:Sulfamethoxypyridazine
CAS:80-35-3
Purity:98%(Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
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Products Intro: Product Name:Sulfamethoxypyridazine
CAS:80-35-3
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
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Products Intro: CAS:80-35-3
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
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Products Intro: Product Name:Sulfamethoxypyridazine
CAS:80-35-3
Company Name: career henan chemical co
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Products Intro: Product Name:Sulfamethoxypyridazine
CAS: 80-35-3
Purity:99% Package:1kg;7USD

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Sulfamethoxypyridazine Basic information
Product Name:Sulfamethoxypyridazine
Synonyms:N1-(6-Methoxy-d3-3-pyridazinyl)sulfanilamide, 4-Amino-N-(6-methoxy-d3-3-pyridazinyl)benzenesulfonamide;Sulfamethoxypyridazine-d3;SULFAMETHOXYPYRIDAZINE;N1-(6-METHOXYPYRIDAZIN-3-YL)SULFANILAMIDE;MIDICEL;3-(4-Aminobenzenesulfonamido)-6-methoxypyridazine;3-(p-Aminobenzenesulfamido)-6-methoxypyridazine;3-Methoxy-6-sulfanilamidopyridazine
CAS:80-35-3
MF:C11H12N4O3S
MW:280.3
EINECS:201-272-5
Product Categories:-;Pyrazine;Amines;Intermediates;Pharmaceuticals;Sulfur & Selenium Compounds;MIDICEL;pharmaceutical
Mol File:80-35-3.mol
Sulfamethoxypyridazine Structure
Sulfamethoxypyridazine Chemical Properties
Melting point 182-183°
density 1.3936 (rough estimate)
refractive index 1.6200 (estimate)
storage temp. 2-8°C
form Crystalline Powder
pka6.7(at 25℃)
color White to yellow
Merck 14,8919
BRN 277076
CAS DataBase Reference80-35-3(CAS DataBase Reference)
NIST Chemistry ReferencePyridazine, sulfamethoxy-(80-35-3)
Safety Information
Hazard Codes Xi
Risk Statements 37/38-41
Safety Statements 26-39
WGK Germany 2
RTECS WP0400000
10
HS Code 29350090
ToxicityLD50 orally in mice: 1750 mg/kg, (Seki)
MSDS Information
Sulfamethoxypyridazine Usage And Synthesis
Chemical PropertiesWhite solid
UsesAntibacterial.
DefinitionChEBI: A sulfonamide consisting of pyridazine having a methoxy substituent at the 6-position and a 4-aminobenzenesulfonamido group at the 3-position.
Brand nameAmidin;Aseptilex;Asey-sulfa;Bimalong;Biocorn;Bio-cron;Bio-pectodil;Davosin suspension;Deltavagin;Desulfon;Durasul jarabe;Elix;Ensulfa;Eusulfa;Exazole;Farinffnicol;Fercasulf;Hesse-sulfon;Ketiak;Kynex acetyl;Lentosulfa;Linder;Logisul jarabe;Longamid;Longisul;Metamit;Metazina;Metuzina;Minikel;Novosulfin;Pirasulfon;Ralenta;Rotardon;S.d.m.;Septotryl;Smop;Sulamin;Sulfa spirig;Sulfabon;Sulfadazina;Sulfadepot;Sulfadin;Sulfadurazin;Sulfaintensa;Sulfakeyn;Sulfametopyridazin;Sulfamizina;Sulfamyd;Sulfapyrazin;Sulfatar;Sulfocidan;Sulfonamid;Sulforetent;Sulfo-rit;Unisulfa dulcis;Uroplex;Velaten;Volocid;Vtg 44.
World Health Organization (WHO)Sulfamethoxypyridazine, a sulfonamide anti-infective agent, was introduced in 1957 for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing bacterial resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Commercial manufacture of the drug has been discontinued by at least one major manufacturer but supplies can still be obtained on special request, particularly for patients with dermatitis herpetiformis in which condition it has been claimed to be beneficial.
Pharmaceutical Applications3-Sulfanilamido-6-methoxypyridazine. Properties are similar to those of sulfadimethoxine. A rapidly absorbed, long-acting compound (half-life 38 h) with a high degree of protein binding (96%). A 1 g oral dose achieves a peak plasma concentration of around 100 mg/L after 5 h. Its use has been largely discontinued because of frequent adverse effects, but there are reports of benefit in dermatitis herpetiformis. It has been used in combination with trimethoprim.
Sulfamethoxypyridazine Preparation Products And Raw materials
Tag:Sulfamethoxypyridazine(80-35-3) Related Product Information
1-(2,6-Dimethylphenoxy)-2-propanamine Sulfanilamide N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO Aniline Thioridazine Sulfadimethoxine AMINO ACIDS Pyridaphenthion 4-Methoxybenzoyl chloride Betaine Sodium sulfamethoxypyridazine (Trifluoromethoxy)benzene ALTRENOGEST Methoxy Anthranilic acid 2-Methoxyethanol Glycine Anisole