| Company Name: |
Beijing Minruida Technology Co., Ltd.
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| Tel: |
010-82387566 18001021521; |
| Email: |
sales@mreda.com.cn |
| Products Intro: |
Product Name:3-Azido-3-deoxythymidine-5-triphosphate
CAS:92586-35-1
Purity:95% Package:5mg
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| | 3'-Azido-3'-deoxythymidine-5'-triphosphate Basic information |
| | 3'-Azido-3'-deoxythymidine-5'-triphosphate Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Methanol (Slightly), Water (Slightly) | | form | Sticky Solid | | color | Off-White | | Stability: | Hygroscopic |
| | 3'-Azido-3'-deoxythymidine-5'-triphosphate Usage And Synthesis |
| Uses | 3'-Azido-3'-deoxythymidine 5’-Triphosphate Tetraammonium Salt, is used for the preparation of drug against human retroviruses. | | Biological Activity | AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is an active triphosphate metabolite of Zidovudine (AZT). It has antiretroviral activity and inhibits HIV replication. | | in vitro | AZT triphosphate causes mitochondrial dysfunction, increases the production of cytotoxic reactive oxygen species (ROS), and impairs the balance of the mitochondrial quality control system in H9c2 cell model established from rat embryonic myoblasts. | | target | HIV
HBV
DNA polymerase
Reactive oxygen species (ROS) |
| | 3'-Azido-3'-deoxythymidine-5'-triphosphate Preparation Products And Raw materials |
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