| Company Name: |
United States Biological
|
| Tel: |
800.520.3011 or 781.639.5092 |
| Email: |
chemicals@usbio.net |
| Products Intro: |
Product Name:Betanidine
CAS:55-73-2
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| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Email: |
enquiry@leancare.co.uk |
| Products Intro: |
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| | Betanidine Basic information |
| Product Name: | Betanidine | | Synonyms: | Betanidine;Bethanidine;1-Benzyl-2,3-dimethylguanidine;N,N'-Dimethyl-N''-(phenylmethyl)guanidine;2-benzyl-1,3-diMethylguanidine;BETANIDIN;Guanidine, N,N''-dimethyl-N'-(phenylmethyl)-;Betanidine USP/EP/BP | | CAS: | 55-73-2 | | MF: | C10H15N3 | | MW: | 177.25 | | EINECS: | | | Product Categories: | | | Mol File: | 55-73-2.mol |  |
| | Betanidine Chemical Properties |
| Melting point | 195-197° | | Boiling point | 299.18°C (rough estimate) | | density | 0.9826 (rough estimate) | | refractive index | 1.4800 (estimate) | | pka | pKa 10.6 (Uncertain) |
| | Betanidine Usage And Synthesis |
| Originator | Bendogen,Lagap
Pharmaceuticals SA | | Uses | Betanidine is a betacyanin and an aglycone of the beet dye betanin. | | Definition | ChEBI: Bethanidine is a member of guanidines. It has a role as an adrenergic antagonist and an antihypertensive agent. | | Manufacturing Process | A mixture of 2-bromobenzylamine (12.5 g) and S-methylthiouronium sulfate
(10 g) in water (20 ml) was heated for 1.5 hours on a steam bath in a hood,
during which methylmercaptan escaped (as evidenced by a foul odour). The
reaction mixture was then cooled and diluted with ethanol (100 ml). A
colourless solid of 2-bromobenzylguanidine sulfate was separeted, and washed
with ethanol. This solid melted at 230-232°C; it was recrystallized from water
and then melted at 247-248°C. By action of a basic agent the salt obtained
may be converted into free base. | | Therapeutic Function | Antihypertensive |
| | Betanidine Preparation Products And Raw materials |
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