5-O-Desmethyl Donepezil

5-O-Desmethyl Donepezil Suppliers list
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:2-[(1-benzylpiperidin-4-yl)methyl]-5-hydroxy-6-methoxy-2,3-dihydroinden-1-one
CAS:120013-57-2
Purity:0.99 Package:5KG;1KG
Company Name: Standardpharm Co. Ltd.
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Products Intro: Product Name:Donepezil Impurity 28
CAS:120013-57-2
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: CR Corporation Lomited
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Email: fred.wen@crcorporation.cn
Products Intro: Product Name:5-O-Desmethyl Donepezil
CAS:120013-57-2
Company Name: Hunan Jibang Biological Technology Co., LTD
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Products Intro: Product Name:2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one hydrochloride
CAS:120013-57-2
Purity:0.98 Package:1G;5G10g;100g
Company Name: China National Standard Pharmaceutical Corporation Limited
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Products Intro: Product Name:Donepezil Impurity 28
CAS:120013-57-2
Purity:0.95 Package:Vials
5-O-Desmethyl Donepezil Basic information
Product Name:5-O-Desmethyl Donepezil
Synonyms:1-Benzyl-4-[(5-hydroxy-6-methoxy-1-oxo-indan-2-yl)methylpiperidine;2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one;2-((1-benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one hydrochloride;Donepezil 5-O-Desmethyl Impurity;Donepezil Impurity 28;Donepezil 5-O-Desmethyl Imp;2-[(1-benzylpiperidin-4-yl)methyl]-5-hydroxy-6-methoxy-2,3-dihydroinden-1-one;1H-Inden-1-one, 2,3-dihydro-5-hydroxy-6-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-
CAS:120013-57-2
MF:C23H27NO3
MW:365.47
EINECS:
Product Categories:Heterocycles;Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:120013-57-2.mol
5-O-Desmethyl Donepezil Structure
5-O-Desmethyl Donepezil Chemical Properties
Melting point 170-172°C
Boiling point 545.3±50.0 °C(Predicted)
density 1.190±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
form Solid
pka8.16±0.40(Predicted)
color White to Pale Brown
CAS DataBase Reference120013-57-2
Safety Information
MSDS Information
5-O-Desmethyl Donepezil Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesA metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.
UsesA metabolite of Donepezil, an inhibitor of acetylcholinesterase
DefinitionChEBI: 5-O-desmethyldonepezil is a member of the class of piperidines that is donepezil in which the 5-methoxy group has been demethylated to the corresponding hydroxy derivative. It is metabolite of donepezil, a drug used in the treatment of dementia. It has a role as a drug metabolite. It is a member of piperidines, a cyclic ketone, an aromatic ether and a member of guaiacols.
5-O-Desmethyl Donepezil Preparation Products And Raw materials
Tag:5-O-Desmethyl Donepezil(120013-57-2) Related Product Information
Donepezil Hydrochloride Donepezil Donepezil Impurity 17 HCl 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine 2-[(1-Benzylpiperidin-4-yl)hydroxyMethyl]-5,6-diMethoxyindan-1-one RAC (CIS/TRANS) DONEPEZIL N-OXIDE XWAIAVWHZJNZQQ-RPXFAUAJSA-N 2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE 3,5-Dichloro-4-hydroxypyridine Donepezil Impurity 6-O-Desmethyl Donepezil β-D-Glucuronide 2-isonicotinoyl-5,6-diMethoxy-2,3-dihydro-1H-inden-1-one 5,6-DIMETHOXY-2-PYRIDIN-4-YLMETHYL-INDAN-1-ONE 5,6-Dimethoxy-1-indanone 4-PYRIDINECARBOXALDEHYDE N-OXIDE Donepezil Impurity 8 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one Dihydro Donepezil (Mixture of Diastereomers)