| Company Name: |
Cato Research Chemicals Inc.
|
| Tel: |
020-81960175 |
| Email: |
min.he@cato-chem.com |
| Products Intro: |
Product Name:Fenofibrate-d6
CAS:1092484-56-4
Purity:95% Package:25Mg, 50Mg
|
| Company Name: |
Artis Biotech Co. Ltd.
|
| Tel: |
19138486554 18582380095 |
| Email: |
sales@artisbio.com |
| Products Intro: |
Product Name:Fenofibrate-d6
CAS:1092484-56-4
Purity:98% HPLC Package:5mg 20mg 50mg 100mg 200mg 1g
|
Fenofibrate-d6 manufacturers
- Fenofibrate-D6
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- $0.00 / 5mg
-
2023-05-27
- CAS:1092484-56-4
- Min. Order: 1mg
- Purity: 96%
- Supply Ability: 50mg
|
| | Fenofibrate-d6 Basic information |
| | Fenofibrate-d6 Chemical Properties |
| Melting point | 70-720C | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Sightly) | | form | Solid | | color | White to Off-White | | CAS DataBase Reference | 1092484-56-4 |
| | Fenofibrate-d6 Usage And Synthesis |
| Description | Fenofibrate-d6 is intended for use as an internal standard for the quantification of fenofibrate by GC- or LC-MS. Fenofibrate is an agonist of peroxisome proliferator-activated receptor α (PPARα) with EC50 values of 18 and 30 μM for mouse and human receptors, respectively, in a transactivation assay. It is selective for PPARα over PPARγ (EC50s = 300 and 200 μM for mouse and human receptors, respectively) and lacks activity at mouse and human PPARδ at a concentration of 100 μM. In vivo, fenofibrate (50-100 mg/kg) reduces plasma levels of triglycerides, C-reactive protein, and malondialdehyde (MDA) in mice with fructose-induced hypertriglycemia in a dose-dependent manner. It decreases glomerular and tubular atrophy and necrosis induced by cisplatin in rat kidney when administered at a dose of 100 mg/kg. Fenofibrate also reduces the number of pulmonary lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in lung of Tsumura Suzuki obese diabetic (TSOD) mice. | | Chemical Properties | White Solid | | Uses | Antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion. |
| | Fenofibrate-d6 Preparation Products And Raw materials |
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