Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Sex Hormone-Binding Globulin Purity:>= 95 % SDS-PAGE, buffered aqueous glycerol solution Package:10μg Remarks:S1437
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Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
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Tel: |
15926423062 |
Email: |
422450190@qq.com |
Products Intro: |
Product Name:Recombinant Human SHBG Protein, His Tag Purity:>90% as determined by SDS-PAGE Package:50μg, 100μg
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Company Name: |
Shanghai Huzhen Industrial Co., LTD
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Tel: |
021-60345367 13916550749 |
Email: |
sales@shzbio.com |
Products Intro: |
Product Name:SHBG Purity:> 99% Package:50ul/RMB 1098;100ul/RMB 1880;200ul/RMB 2900 Remarks:Sex Hormone Binding Globulin; ABP; Androgen binding protein
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| SEX HORMONE BINDING GLOBULIN Basic information |
Product Name: | SEX HORMONE BINDING GLOBULIN | Synonyms: | HTEBG;HSHBG;TEBG;TESTOSTERONE-OESTRADIOL BINDING GLOBULIN, HUMAN;TESTOSTERONE-ESTRADIOL BINDING GLOBULIN;TESTOSTERONE-ESTRADIOL BINDING GLOBULIN, HUMAN;SEX HORMONE BINDING GLOBULIN;SEX HORMONE BINDING GLOBULIN, HUMAN | CAS: | | MF: | | MW: | 612.74 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| SEX HORMONE BINDING GLOBULIN Chemical Properties |
storage temp. | −20°C | form | buffered aqueous glycerol solution |
Hazard Codes | B | WGK Germany | 1 |
| SEX HORMONE BINDING GLOBULIN Usage And Synthesis |
Uses | Sex hormone binding globulin (SHBG) from human serum has been used as a spiked sample in radioimmunoassay. It may also be used to study the effects of hydroxylated estrogen metabolites (2-OH-E2 and 4-OH-E2) on the mRNA and protein expression of SHBG in MCF-7 human breast cancer cell line. | General Description | Sex hormone binding globulin (SHBG) is secreted by the liver. It is also expressed in the endometrium, ovary and testis. SHBG is composed of 402 amino acids and the gene encoding it is localized on human chromosome 17p12–p13. | Biochem/physiol Actions | Sex hormone binding globulin (SHBG) is a dimeric plasma glycoprotein with high affinity for the gonadal steroids, testosterone and estradiol. It regulates the availability of sex steroid hormones and limits their access to target cells. SHBG also inhibits estradiol-induced proliferation of breast cancer cells. Alterations in the expression of the protein have been linked to male infertility. |
| SEX HORMONE BINDING GLOBULIN Preparation Products And Raw materials |
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