| Company Name: |
DC Chemicals
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| Tel: |
021-58447131 13564518121 |
| Email: |
sales@dcchemicals.com |
| Products Intro: |
Product Name:(+)-Penbutolol ((R)-Penbutolol; (+)-Isopenbutolol)
CAS:38363-41-6
Purity:98% HPLC Package:100mg，250mg，1g
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:(+)-Penbutolol ((R)-Penbutolol;(+)-Isopenbutolol)
CAS:38363-41-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | Isopenbutolol Basic information |
| Product Name: | Isopenbutolol | | Synonyms: | d-Penbutolol;Isopenbutolol;(2R)-1-(tert-Butylamino)-3-(2-cyclopentylphenoxy)-2-propanol;[R,(+)]-1-(tert-Butylamino)-3-(2-cyclopentylphenoxy)-2-propanol;Ccris 2854;R-(+)-Isopenbutolol;(+)-(R)-Penbutolol;(+)-Isopenbutolol | | CAS: | 38363-41-6 | | MF: | C18H29NO2 | | MW: | 291.43 | | EINECS: | | | Product Categories: | | | Mol File: | 38363-41-6.mol |  |
| | Isopenbutolol Chemical Properties |
| Boiling point | 438.2±40.0 °C(Predicted) | | density | 1.030±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 13.90±0.20(Predicted) |
| | Isopenbutolol Usage And Synthesis |
| Definition | ChEBI: (+)-Penbutolol is an aromatic ether. | | Biological Activity | Isopenbutololl is a beta-adrenergic antagonist with an IC50 value of 0.74 μM. It is also an optical isomer of (-)-penbutolol, which blocks Na+ channels. | | in vitro | (+)-penbutolol on the [Ca 2+ ] i -increase induced by LPC is concentration-dependent.
(+) -penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10 -6 M, 5×10 -6 M and 10 -5 M, respectively). | | target | IC50: 0.74 μM (β-adrenoceptor). |
| | Isopenbutolol Preparation Products And Raw materials |
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