| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:SOS1-IN-7
CAS:2755415-30-4
Package:25mg/RMB 14900;50mg/RMB 19420;100mg/RMB 24625
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Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- manufacturers
- SOS1-IN-7
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- $2140.00 / 25mg
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2025-10-27
- CAS:2755415-30-4
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Basic information |
| | Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Chemical Properties |
| Boiling point | 609.0±65.0 °C(Predicted) | | density | 1.48±0.1 g/cm3(Predicted) | | pka | 12.55±0.40(Predicted) |
| | Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Usage And Synthesis |
| Uses | SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC50s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively[1]. | | IC 50 | SOS1-G12D: 20 nM (IC50); SOS1-G12V: 67 nM (IC50) | | References | [1] Pyridine-pyrimidine derivative, preparation method therefor and pharmaceutical use thereof. WO2021249519A1. |
| | Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl- Preparation Products And Raw materials |
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