Glycine, N,N′-[2-[(4-fluorophenyl)methoxy]-1,4-phenylene]bis[N-[(4-methylphenyl)sulfonyl]-

Glycine, N,N′-[2-[(4-fluorophenyl)methoxy]-1,4-phenylene]bis[N-[(4-methylphenyl)sulfonyl]- Suppliers list

Company Name:	Shanghai Beckham Medical Technology Co., Ltd
Tel:	13816613772
Email:	huahero21@sina.com
Products Intro:	Product Name:Keap1-Nrf2-IN-7 CAS:2769963-42-8 Purity:98% HPLC Package:1g

Glycine, N,N′-[2-[(4-fluorophenyl)methoxy]-1,4-phenylene]bis[N-[(4-methylphenyl)sulfonyl]- Basic information

Product Name:	Glycine, N,N′-[2-[(4-fluorophenyl)methoxy]-1,4-phenylene]bis[N-[(4-methylphenyl)sulfonyl]-
Synonyms:	Glycine, N,N′-[2-[(4-fluorophenyl)methoxy]-1,4-phenylene]bis[N-[(4-methylphenyl)sulfonyl]-;Keap1-Nrf2-IN-7
CAS:	2769963-42-8
MF:	C31H29FN2O9S2
MW:	656.7
EINECS:
Product Categories:
Mol File:	2769963-42-8.mol

Glycine, N,N′-[2-[(4-fluorophenyl)methoxy]-1,4-phenylene]bis[N-[(4-methylphenyl)sulfonyl]- Chemical Properties

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Glycine, N,N′-[2-[(4-fluorophenyl)methoxy]-1,4-phenylene]bis[N-[(4-methylphenyl)sulfonyl]- Usage And Synthesis

Uses	Keap1-Nrf2-IN-7 (compound 7v) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein?protein interaction) inhibitor with an IC50 of 0.45 μM[1].
References	[1] Lee S, et al. Structure-activity relationships of 1,4-bis(arylsulfonamido)-benzene or naphthalene-N,N'-diacetic acids with varying C2-substituents as inhibitors of Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2022 Jul 5;237:114380. DOI:10.1016/j.ejmech.2022.114380

Glycine, N,N′-[2-[(4-fluorophenyl)methoxy]-1,4-phenylene]bis[N-[(4-methylphenyl)sulfonyl]- Preparation Products And Raw materials

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