| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Vanoxonin
CAS:86933-99-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Vanoxonin;Vanoxonin
CAS:86933-99-5
Purity:98% Package:1 mg
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| | vanoxonin Basic information |
| Product Name: | vanoxonin | | Synonyms: | vanoxonin;(+)-N-(2,3-Dihydroxybenzoyl)-L-Thr-N5-Ac-N5-hydroxy-L-Orn-OH;Antibitic MG-245CF2A;N5-Acetyl-N2-[N-(2,3-dihydroxybenzoyl)-L-threonyl]-N5-hydroxy-L-ornithine;Antibiotic MG 245CF2A;MG-245-CF2-A;N-(2,3-dihydroxybenzoyl)-L-threonyl-N5-acetyl-N5-hydroxy-L-ornithine | | CAS: | 86933-99-5 | | MF: | C18H25N3O9 | | MW: | 427.408 | | EINECS: | | | Product Categories: | | | Mol File: | 86933-99-5.mol |  |
| | vanoxonin Chemical Properties |
| storage temp. | -20°C | | form | A solid |
| | vanoxonin Usage And Synthesis |
| Biological Activity | Vanoxonin is a bacterial metabolite that has been found in S. hirsuta.1 It forms a complex with vanadium, and the complex inhibits thymidylate synthetase with an IC50 value of 0.7 μg/ml. The vanoxonin-vanadium complex is cytotoxic to L1210 leukemia cells (MIC = 25 μg/ml) and increases survival in Ehrlich murine spontaneous adenocarcinoma and L1210 mouse tumor models. | | References | 1.Kanai, F., Sawa, T., Hamada, M., et al.Vanoxonin, a new inhibitor of thymidylate synthetaseJ. Antibiot. (Tokyo)36(6)656-660(1983) |
| | vanoxonin Preparation Products And Raw materials |
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