| Company Name: |
Shanghai AQBioPharma Co., Ltd.
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| Tel: |
13764862135 |
| Email: |
yaoliang.ni@aqbiopharma.com.cn |
| Products Intro: |
Product Name:N,N 0-Disalicylidene-1,2-ethanediaminato-(2-)]manganese(III) Chloride
CAS:53177-12-1
Purity:97% Package:500g;1kg;25kg;50kg;100kg;1T
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:EUK-8
CAS:53177-12-1
Purity:>=95% (HPLC) Package:10MG Remarks:SML0742-10MG
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| | N,N'-bis(salicylideneamino)ethane-manganese(II) Basic information |
| Product Name: | N,N'-bis(salicylideneamino)ethane-manganese(II) | | Synonyms: | N,N'-Bis(salicylidene)-1,2-ethylenediamine-manganese(II)
(SP-5-13)-Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-alphaN)methylidyne]]bis[phenolato-alphaO]](2-)]manganese;(Salen)manganese(III) chloride;(SP-5-13)-Chloro[[2,2′-[1,2-ethanediylbis(nitrilomethylidyne)]bis[phenolato]](2-)-N,N′,O,O′]-manganese;Chloro(bis(salicylidene)ethylenediamine)manganese;Chloro[N,N′-ethylenebis(salicylideneaminato)]manganese;Manganese(salen) chloride;N,N'-bis(salicylideneamino)ethane-manganese(II);EUK-8 | | CAS: | 53177-12-1 | | MF: | C16H14ClMnN2O2 | | MW: | 356.685609 | | EINECS: | | | Product Categories: | | | Mol File: | 53177-12-1.mol |  |
| | N,N'-bis(salicylideneamino)ethane-manganese(II) Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: soluble1mg/mL, clear | | form | powder | | color | faint to very dark brown |
| | N,N'-bis(salicylideneamino)ethane-manganese(II) Usage And Synthesis |
| Uses | [N,N 0-Disalicylidene-1,2-ethanediaminato-(2-)]manganese(III) Chloride is an oxidation catalysts and an enzyme mimetic. It also functions as an intermediate in the synthesis of manganese(III) complexes with fluorinated salen derivatives that exhibits antioxidant properties. | | Biochem/physiol Actions | EUK-8 is a salen manganese complex that exhibit potent antioxidant activities. EUK-8 is a superoxide dismutase (SOD) that inhibits amyloid fibril formation, including islet amyloid polypeptide (IAPP), β-amyloid and lysozyme amyloid aggregation. It appears that EUK-8 disrupts the pre-formed amyloid fibrils. EUK-8 increases the viability of the SK-N-MC cells exposed to preformed IAPP fibrils. |
| | N,N'-bis(salicylideneamino)ethane-manganese(II) Preparation Products And Raw materials |
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