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| | 4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE Basic information |
| Product Name: | 4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE | | Synonyms: | CHLOROMETHYLTHIAZOLE-4 HCL;4-(CHLOROMETHYL)-1,3-THIAZOLE;4-(CHLOROMETHYL)-1,3-THIAZOLE HYDROCHLORIDE;4-CHLOROMETHYL-THIAZOLE;4-(CHLOROMETHYL)THIAZOLE HCL;4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE;4-ChloroMethylthiazoliuM hydrochloride;4-chloroMethythiazole hydrochloride | | CAS: | 7709-58-2 | | MF: | C4H5Cl2NS | | MW: | 170.06 | | EINECS: | 672-064-3 | | Product Categories: | API intermediates;john's | | Mol File: | 7709-58-2.mol |  |
| | 4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE Chemical Properties |
| Melting point | 166-167 °C (sublm) | | storage temp. | Inert atmosphere,Room Temperature | | form | powder to crystal | | color | White to Light yellow | | InChIKey | NVTBASMQHFMANH-UHFFFAOYSA-N | | CAS DataBase Reference | 7709-58-2(CAS DataBase Reference) |
| | 4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | White crystalline | | Uses | 4-(Chloromethyl)thiazole hydrochloride and its derivatives can be used to prepare 4-thiazole carboxylic acid. It has been shown that in the study of synthesis of conformationally restricted RGD-containing integrin ligands by efficient solid-phase intramolecular thioalkylation, the reaction of S-nucleophiles with the newly generated N-terminal 4-chloromethyl thiazoles afforded the desired cyclic RGD product 5 with high purity and good overall yield[1]. | | References | [1] ADEL NEFZI Jason E F. N-terminus 4-chloromethyl thiazole peptide as a macrocyclization tool in the synthesis of cyclic peptides: application to the synthesis of conformationally constrained RGD-containing integrin ligands[J]. Tetrahedron Letters, 2011. DOI:10.1016/j.tetlet.2010.12.043. |
| | 4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE Preparation Products And Raw materials |
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