- N-isopropyl-4-piperidone
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- $200.00 / 25KG
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2024-04-19
- CAS:5355-68-0
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 2MT per month
- N-isopropyl-4-piperidone
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- $150.00 / 1KG
-
2024-04-19
- CAS:5355-68-0
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1MT per month
- 1-Isopropyl-4-piperidone
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- $110.00/ kilogram
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2024-01-04
- CAS:5355-68-0
- Min. Order: 1kilogram
- Purity: 99%
- Supply Ability: 10 tons/per week
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| | 1-Isopropyl-4-piperidone Basic information |
| Product Name: | 1-Isopropyl-4-piperidone | | Synonyms: | 1-(1'-METHYLETHYL)-4-PIPERIDONE;1-ISOPROPYL-4-PIPERIDONE;1-ISOPROPYL-PIPERIDIN-4-ONE;TIMTEC-BB SBB005846;1-Isopropyl-4-piperidinone;4-Piperidinone, 1-(1-methylethyl)-;4-Piperidinone,1-(1-methylethyl)-;4-Piperidone, 1-isopropyl- | | CAS: | 5355-68-0 | | MF: | C8H15NO | | MW: | 141.21 | | EINECS: | 226-339-6 | | Product Categories: | Piperidine;Heterocyclic Compounds | | Mol File: | 5355-68-0.mol |  |
| | 1-Isopropyl-4-piperidone Chemical Properties |
| Melting point | 105-105.5 °C | | Boiling point | 100-101 °C (27 mmHg) | | density | 0.95 | | refractive index | 1.465-1.467 | | Fp | 100-101°C/27mm | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 8.18±0.20(Predicted) | | form | clear liquid | | color | Colorless to Brown | | BRN | 107857 | | InChI | InChI=1S/C8H15NO/c1-7(2)9-5-3-8(10)4-6-9/h7H,3-6H2,1-2H3 | | InChIKey | CCDBCHAQIXKJCG-UHFFFAOYSA-N | | SMILES | N1(C(C)C)CCC(=O)CC1 | | CAS DataBase Reference | 5355-68-0(CAS DataBase Reference) | | NIST Chemistry Reference | N-isopropyl-4-piperidone(5355-68-0) |
| | 1-Isopropyl-4-piperidone Usage And Synthesis |
| Chemical Properties | CLEAR YELLOW TO BROWN LIQUID | | Uses | Used as a pharmaceutical intermediate. | | Synthesis | Preparation of 1-Isopropyl-4-piperidone: Potassium carbonate (4.2 g, 31.1 mmol) was added into a solution of isopropylamine (2.1 mL, 3.3 mmol) in ethanol (10 mL) and the resulting mixture was heated at 75 °C. A solution of 1,1-dimethyl-4-oxopiperidinium iodide (4.0 g, 15.5 mmol) in water (5 mL) was added over a period of 30 minutes. The reaction mixture was stirred 1 hour at 75 °C, and then 12 hours at room temperature. The reaction mixture was concentrated under reduced pressure. The residue was taken up with water (25 mL) and extracted with dichloromethane (25 mL). The organic layer was dried (Na2SO4) and concentrated under vacuum. a colourless oil (1.5 g, 69 %). 1H NMR (DMSO-d6, 400 MHz): δ 2.89-2.83 (m, 1 H), 2.67 (t, J=5.9 Hz, 4H), 2.29 (t, J=5.9 Hz, 4H), 0.98 (d, J=6.5 Hz, 6H). LCMS (Method C): Mass found (M+ 142.2), Rt (min): 0.63, Area (%): 99.4 (Max. Chrom.).
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| | 1-Isopropyl-4-piperidone Preparation Products And Raw materials |
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