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| | PAROXETINE-D4 HCL Basic information |
| Product Name: | PAROXETINE-D4 HCL | | Synonyms: | Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S,4R)- (9CI);Paroxetine Hydrochloride (350 mg);Paroxetine Hydrochloride (350 mg)G0D0030.972mg/mg(ai);PAROXETINE-D4 HCL;PAROXETINE HYDROCHLORIDE 1/2H2O;Piperidine,3-[(1,3-benzodioxol-5-yloxy)Methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate(2:2:1), (3S,4R)-;Paroxetine hydrochloride
(3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride;Paroxetine hydrochloride hemihydrate, >=99% | | CAS: | 110429-35-1 | | MF: | C19H23ClFNO4 | | MW: | 383.84 | | EINECS: | 000-000-0 | | Product Categories: | Active Pharmaceutical Ingredients;Cnbio;Serotonin | | Mol File: | 110429-35-1.mol |  |
| | PAROXETINE-D4 HCL Chemical Properties |
| Melting point | 121-131 C | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Slightly soluble in water, freely soluble in methanol, sparingly soluble in ethanol (96 per cent) and in methylene chloride. | | form | powder | | color | white | | λmax | 292nm(H2O)(lit.) | | Merck | 14,7043 | | CAS DataBase Reference | 110429-35-1 |
| | PAROXETINE-D4 HCL Usage And Synthesis |
| Chemical Properties | White or almost white, crystalline powder. | | Uses | Antidepressant;5-HT uptake inhibitor | | Uses | Paroxetine hydrochloride hemihydrate has been used: as an antidepressant to study its effects on neural stem cells (NSCs) from embryonic rat hippocampus in vitro; as a CYP 2D6 inhibitor to study its effects on the in vitro?production by human recombinant CYP 2D6 of the phenolic metabolites; as an antidepressant to study its effects on the expression of pituitary adenylate cyclase activating polypeptide (PACAP), its receptors and brain-derived neurotrophic factor (BDNF) in rat primary hippocampal neurons | | Uses | Paroxetine Hydrochloride, is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). | | General Description | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards | | Biochem/physiol Actions | Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant |
| | PAROXETINE-D4 HCL Preparation Products And Raw materials |
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