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| | 6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER Basic information |
| Product Name: | 6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER | | Synonyms: | 6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER;Xanthylium, 9-2-carboxy-4-(2,5-dioxo-1-pyrrolidinyl)oxycarbonylphenyl-3,6-bis(dimethylamino)-, inner salt;5-Carboxytetramethylrhodamine succinimidyl ester;5-TAMRASE;"4-Carboxytetramethylrhodamine N-succinimidyl ester";5-TAMRA-SEor5-TAMRA-NHS;5-TAMRA N-Succinimidyl Ester;2-[6-(Dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl]-5-[[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl]benzoate | | CAS: | 150810-68-7 | | MF: | C29H25N3O7 | | MW: | 527.53 | | EINECS: | | | Product Categories: | FLUOROPHORES | | Mol File: | 150810-68-7.mol |  |
| | 6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | DMF: soluble | | form | A solid | | InChIKey | VWFRSNKRTNUMET-UHFFFAOYSA-N |
| WGK Germany | 3 | | HS Code | 32049010 |
| | 6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER Usage And Synthesis |
| Description | 5-Carboxytetramethylrhodamine succinimidyl ester (5-TAMRA-SE) is an amine-reactive fluorescent probe. It has been used in double site-directed peptide modification to label proteinase substrates for use in FRET assays. It quenches lucifer yellow CH fluorescence by greater than 90% in uncleaved proteinase substrates, which allows for the detection of enzyme-cleaved substrates by an increase in fluorescence intensity. It has also been used in the synthesis of fluorescent derivatives of a variety of compounds, including the antibiotic ampicillin , nucleotide diphosphate uridine-5’-diphosphate (UDP; ), and the progesterone receptor antagonist RU486 (mifepristone; ). 5-TAMRA-SE displays excitation maxima ranging from 540 to 560 nm and an emission maximum of 580 nm. | | Uses | Amine-Reactive Fluorescent Probe for labeling of DNA and RNA | | Uses | Amine-reactive form of 5-carboxytetramethylrhodamine single isomer. | | storage | Store at -20°C |
| | 6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER Preparation Products And Raw materials |
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