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Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Suppliers list
Company Name: HEBEI BRANT PHARMACEUTICAL CO.,LTD
Tel: +86-86-31184455288 +8617736059406
Email: rice@brantpharm.com
Products Intro: Product Name:2-(3-formyl-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylat
CAS:161798-01-2
Purity:>=99.0% Package:100kg|500kg|1000kg
Company Name: Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd
Tel: +86-010-83386758 +86-18810831598
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Products Intro: Product Name:2-(3-Formyl-4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid ethyl ester
CAS:161798-01-2
Purity:0.99 Package:25KG;1KG
Company Name: Jinan Jianfeng Chemical Co., Ltd
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Products Intro: Product Name:ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
CAS:161798-01-2
Purity:99%min Package:1kg|10kg|100kg Remarks:pharm intermediate
Company Name: Hebei Yanxi Chemical Co., Ltd.
Tel: +8617531190177
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Products Intro: Product Name:ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
CAS:161798-01-2
Purity:0.99 Package:1kg Remarks:Factory direct sales
Company Name: Anhui Ruihan Technology Co., Ltd
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Products Intro: Product Name:ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
CAS:161798-01-2
Purity:99% Package:1kg;50USD

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate manufacturers

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Basic information
Product Name:Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Synonyms:ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate;2-(3-Formyl-4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester;Thiazolecarboxylicacid,2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-,ethylester;5-carboxylato-1-ethyl-2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-1H-1$l^{4},3-thiazol-1-yl;Ethyl 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylate;5-carboxylato-1-ethyl-2-(3-forMyl-4-h;5-Thiazolecarboxylicacid, 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-, ethyl ester;2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
CAS:161798-01-2
MF:C14H13NO4S
MW:291.32
EINECS:692-179-2
Product Categories:Febuxostat intermediate;161798-01-2
Mol File:161798-01-2.mol
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Structure
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Chemical Properties
Melting point 116 °C
Boiling point 446.7±55.0 °C(Predicted)
density 1.335
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka6.81±0.20(Predicted)
color Pale Yellow to Yellow
InChIInChI=1S/C14H13NO4S/c1-3-19-14(18)12-8(2)15-13(20-12)9-4-5-11(17)10(6-9)7-16/h4-7,17H,3H2,1-2H3
InChIKeyNJRGQNNSIAFIJC-UHFFFAOYSA-N
SMILESS1C(C(OCC)=O)=C(C)N=C1C1=CC=C(O)C(C=O)=C1
CAS DataBase Reference161798-01-2(CAS DataBase Reference)
Safety Information
HS Code 2934100090
MSDS Information
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Usage And Synthesis
DescriptionEthyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate is a pharmaceutical intermediate used in the preparation of the xanthine oxidase inhibitor febuxostat, which is used in the treatment of hyperuricaemia and gout. It is also used in the synthesis of novel thiazolyl α-aminophosphonates.
Chemical PropertiesYellow or yellow powder
UsesEthyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate is a product prepared via reaction 4-Hydroxybenzene-1-benzothiomide with ethyl-2-chloro acetoacetate. An antibacterial agent and antifungal activity against C.albicans.
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Preparation Products And Raw materials
Preparation ProductsEthyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
Tag:Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(161798-01-2) Related Product Information
Febuxostat Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 5,5'-DiMethyl Ester Febuxostat Impurity 14 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 6 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 2-[3-Carboxy-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 8 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate 3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide Ethyl 2-(3-bromo-4-isobutoxyphenyl)- 4-methyl-5-thiazolecarboxylate 4-HYDROXYTHIOBENZAMIDE ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate