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α-Chloromethyl-2-nitro-1H-imidazole-1-ethanol

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α-Chloromethyl-2-nitro-1H-imidazole-1-ethanol Basic information
Product Name:α-Chloromethyl-2-nitro-1H-imidazole-1-ethanol
Synonyms:Ro 7-0269;Ro-07-0269;α-(Chloromethyl)-2-nitro-1H-imidazole-1-ethanol;α-Chloromethyl-2-nitro-1H-imidazole-1-ethanol;1H-Imidazole-1-ethanol, α-(chloromethyl)-2-nitro-;1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole
CAS:13551-86-5
MF:C6H8ClN3O3
MW:205.6
EINECS:
Product Categories:
Mol File:13551-86-5.mol
α-Chloromethyl-2-nitro-1H-imidazole-1-ethanol Structure
α-Chloromethyl-2-nitro-1H-imidazole-1-ethanol Chemical Properties
Melting point 156-158 °C
Boiling point 439.8±55.0 °C(Predicted)
density 1.60±0.1 g/cm3(Predicted)
pka13.08±0.20(Predicted)
Safety Information
MSDS Information
α-Chloromethyl-2-nitro-1H-imidazole-1-ethanol Usage And Synthesis
Uses1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole is an intermediate in the synthesis of 1-(2,3-Epoxypropyl)-2-nitroimidazole (B592583) which is an intermediate in the synthesis of Pimonidazole-d10 (P447814). Isotope labelled Pimonidazole (P447813) is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It abels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.
α-Chloromethyl-2-nitro-1H-imidazole-1-ethanol Preparation Products And Raw materials
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