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| | Matridin-15-one, (5.beta.,7.beta.,11.alpha.)- Basic information |
| Product Name: | Matridin-15-one, (5.beta.,7.beta.,11.alpha.)- | | Synonyms: | Aids087429;Aids-087429;Isoleontine;Leontine;Matridin-15-one, (5.beta.,7.beta.,11.alpha.)-;ALLOMATRINE(RG);1H,5H,10H-Dipyrido[2,1-F:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, (7ar,13as,13bs,13cs)-;(-)-Allomatrine | | CAS: | 6783-60-4 | | MF: | C15H24N2O | | MW: | 248.36 | | EINECS: | | | Product Categories: | | | Mol File: | 6783-60-4.mol |  |
| | Matridin-15-one, (5.beta.,7.beta.,11.alpha.)- Chemical Properties |
| Melting point | 107～108℃ | | Boiling point | 190-210 °C(Press: 7 Torr) | | density | 1.16±0.1 g/cm3(Predicted) | | pka | 9.47±0.20(Predicted) |
| | Matridin-15-one, (5.beta.,7.beta.,11.alpha.)- Usage And Synthesis |
| Description | A tetracyclic alkaloid present in Leontice Eversmanii Bge. this base is laevorotatory with [α]D - 7S.2°. It gives crystallines salts, e.g. the perchlorate, m.p.
252°C; methiodide, m.p. 297°C and the picrate as yellow needles, m.p.
177-9°C. The structure has been determined from the NMR and mass spectra.
The optically inactive form has been synthesized and has m.p. S5-7° C, giving a
crystalline hydrochloride, m.p. 215-7° C. | | References | Platonova, Kuzovkov, Massagetov., 1. Gen. Chern. USSR, 23,880 (1953)
Rulko, Proskurnina., ibid, 31, 308 (1961)
Synthesis:
Mandell et ai., 1. A mer. Chern. Soc., 87, 5234 (1965) |
| | Matridin-15-one, (5.beta.,7.beta.,11.alpha.)- Preparation Products And Raw materials |
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