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| | [Ala17]-MCH Basic information |
| Product Name: | [Ala17]-MCH | | Synonyms: | [Ala17]-MCH;Melanin-concentrating hormone (human), 17-L-alanine- (9CI) | | CAS: | 359784-84-2 | | MF: | C97H155N29O26S4 | | MW: | 2271.7073 | | EINECS: | | | Product Categories: | | | Mol File: | 359784-84-2.mol | ![[Ala17]-MCH Structure](CAS/20180808/GIF/359784-84-2.gif) |
| | [Ala17]-MCH Chemical Properties |
| density | 1.49±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | form | Powder | | color | White to off-white | | Water Solubility | Soluble to 2 mg/ml in water | | Sequence | Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Ala-Gln-Val (Disulfide bridge:Cys7-Cys16) |
| | [Ala17]-MCH Usage And Synthesis |
| Uses | [Ala17]-MCH, a MCH analogue (HY-P1525A), is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM). [Eu3+ chelate-labeled [Ala17]-MCH shows high affnity for MCHR1 (Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2[1]. | | References | [1] Xiaoying Gao, et al. Europium-labeled melanin-concentrating hormone analogues: ligands for measuring binding to melanin-concentrating hormone receptors 1 and 2. Anal Biochem. 2004 May 15;328(2):187-95. DOI:10.1016/j.ab.2004.01.017 |
| | [Ala17]-MCH Preparation Products And Raw materials |
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